Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blind Procedures02:07

Blind Procedures

13.6K
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
13.6K
Protein-protein Interfaces02:04

Protein-protein Interfaces

14.8K
Many proteins form complexes to carry out their functions, making protein-protein interactions (PPIs) essential for an organism's survival. Most PPIs are stabilized by numerous weak noncovalent chemical forces. The physical shape of the interfaces determines the way two proteins interact. Many globular proteins have closely-matching shapes on their surfaces, which form a large number of weak bonds. Additionally, many PPIs occur between two helices or between a surface cleft and a...
14.8K
Protein and Protein Structure02:15

Protein and Protein Structure

88.2K
Proteins are one of the most abundant organic molecules in living systems and have the most diverse range of functions of all macromolecules. Proteins may be structural, regulatory, contractile, or protective. They may serve in transport, storage, or membranes; or they may be toxins or enzymes. Their structures, like their functions, vary greatly. They are all, however, amino acid polymers arranged in a linear sequence.
A protein's shape is critical to its function. For example, an enzyme...
88.2K
Handwashing II: Pre-procedure and Initial Procedure Steps01:19

Handwashing II: Pre-procedure and Initial Procedure Steps

1.6K
The pre-procedure steps of handwashing include removing jewelry and rolling up sleeves. However, many organizations allow staff to wear wedding rings.
The hand washing procedure itself includes the following steps. First, cover cuts, if any, on hands with a waterproof dressing. Cuts and abrasions can become contaminated with bacteria hindering the ability to clean the area thoroughly. In addition, repeated hand washing can worsen an injury.  The nails must be short and clean, without nail...
1.6K
Handwashing III: During the Procedure and Post-Procedure Steps01:15

Handwashing III: During the Procedure and Post-Procedure Steps

2.4K
To wash hands properly, follow these steps:
2.4K
Conservation of Protein Domains Over Different Proteins02:26

Conservation of Protein Domains Over Different Proteins

14.6K
Protein domains are small structurally independent units that are part of a single amino acid chain.  Although these domains are often structurally independent, they may rely on synergistic effects to perform their functions as part of a larger protein. Protein domains may be conserved within the same organism, as well as across different organisms.
A limited set of protein domains often duplicate and recombine during evolution. These domains can be organized in different combinations to...
14.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dark shadows of screen: How Dark Tetrad traits, social identity, and binge-watching fuel digital fatigue.

Acta psychologicaยท2026
Same author

Amino alkyl-alkyl/aryl sulphides (DRDE-07 and analogues) as promising cytoprotectants for sulphur and nitrogen mustards - A review.

Toxicology reportsยท2025
Same author

Oxygen vacancies mediated enhanced photocatalytic activity of band gap engineered BaSn<sub>1-<i>x</i></sub> Cu <sub><i>x</i></sub> O<sub>3</sub> towards methylene blue degradation under visible and sunlight.

RSC advancesยท2025
Same author

Exploring workplace spirituality, mindfulness, digital technology, and psychological well-being: A complex interplay in organizational contexts.

Acta psychologicaยท2024
Same author

Probing the molecular interactions between cholinium-based ionic liquids and insulin aspart: A combined computational and experimental study.

International journal of biological macromoleculesยท2023
Same author

Spectrophotometric Analysis of Fluoride Concentration in Dentifrices for Children in India.

Journal of pharmacy & bioallied sciencesยท2022

Related Experiment Video

Updated: Feb 8, 2026

Staining of Proteins in Gels with Coomassie G-250 without Organic Solvent and Acetic Acid
07:47

Staining of Proteins in Gels with Coomassie G-250 without Organic Solvent and Acetic Acid

Published on: August 14, 2009

54.8K

Protein loosing enteropathy after Fontan procedure.

R Vijayaraghavan1, W Y Thay2

  • 1Hospital Tawau, Department of Paediatrics, Sabah, Malaysia. rvijayr99@yahoo.com.

The Medical Journal of Malaysia
|July 3, 2018
PubMed
Summary

The Fontan procedure improves quality of life for complex cyanotic heart diseases, with a 2.1% mortality rate. Long-term survival is achievable, but complications like protein-losing enteropathy require careful management.

More Related Videos

Green Fluorescent Protein-based Expression Screening of Membrane Proteins in Escherichia coli
08:46

Green Fluorescent Protein-based Expression Screening of Membrane Proteins in Escherichia coli

Published on: January 6, 2015

33.6K
Analysis of Protein Folding, Transport, and Degradation in Living Cells by Radioactive Pulse Chase
08:59

Analysis of Protein Folding, Transport, and Degradation in Living Cells by Radioactive Pulse Chase

Published on: February 12, 2019

11.9K

Related Experiment Videos

Last Updated: Feb 8, 2026

Staining of Proteins in Gels with Coomassie G-250 without Organic Solvent and Acetic Acid
07:47

Staining of Proteins in Gels with Coomassie G-250 without Organic Solvent and Acetic Acid

Published on: August 14, 2009

54.8K
Green Fluorescent Protein-based Expression Screening of Membrane Proteins in Escherichia coli
08:46

Green Fluorescent Protein-based Expression Screening of Membrane Proteins in Escherichia coli

Published on: January 6, 2015

33.6K
Analysis of Protein Folding, Transport, and Degradation in Living Cells by Radioactive Pulse Chase
08:59

Analysis of Protein Folding, Transport, and Degradation in Living Cells by Radioactive Pulse Chase

Published on: February 12, 2019

11.9K

Area of Science:

  • Cardiology
  • Pediatric Cardiology
  • Congenital Heart Disease Management

Background:

  • The Fontan procedure, developed in 1971, is a palliative surgery for complex cyanotic heart diseases.
  • It has undergone modifications to enhance patient outcomes and long-term survival.

Observation:

  • The procedure demonstrates a 2.1% mortality rate.
  • Survival rates at 5, 10, 15, and 20 years are 91%, 80%, 73%, and 69%, respectively.
  • Complications include protein-losing enteropathy, reduced exercise capacity, and thromboembolism.

Findings:

  • Protein-losing enteropathy presents with pleural effusion, ascites, and edema.
  • Management of protein-losing enteropathy necessitates regular albumin replacement and close monitoring.
  • Effective management is crucial for reducing mortality and improving quality of life.

Implications:

  • Optimizing the Fontan procedure and its management can significantly improve long-term outcomes for patients.
  • District-level hospitals require support systems for managing these complex cardiac patients.
  • Continued research into mitigating complications is essential for advancing palliative cardiac care.