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Updated: Feb 8, 2026

Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS
Published on: November 8, 2015
Sensorineural Deafness Following Tacrolimus Use
Boju Sangeetha Lakshmi1, Bhukya Vidya, Mogili Hari Krishna Reddy
1From the Department of Nephrology, Sri Venkateswar Institute of Medical Sciences, Tirupati, India.
Abstract:
Early trials of tacrolimus in renal transplant recipients have not revealed hearing loss as an adverse effect. Here, we present a case report and a review of the literature of deafness after tacrolimus use. The review of the literature and our experience suggested that the possible reason for hearing loss could be due to an initiation of a sudden spike in the tacrolimus serum level, which was later worsened by its cumulative toxic effect.
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