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Evaluation of blood pressure in children with idiopathic overactive bladder syndrome
Parsa Yousefichaijan1, Ali Khosrobeigi2, Manochehr Soltani3
1Department of Pediatric Nephrology, Clinical Research Development Center, Amirkabir Hospital, Arak University of Medical Sciences, Arak, Iran.
Insights
Children with overactive bladder syndrome have higher blood pressure (BP). This study found significantly elevated systolic and diastolic BP in children diagnosed with this condition compared to healthy controls.
Area of Science:
- Pediatric Nephrology
- Urology
- Cardiovascular Health
Background:
- Overactive bladder (OAB) in children presents with urinary frequency, urgency, and incontinence.
- OAB is characterized by a functionally smaller bladder with uncontrolled contractions.
- The relationship between OAB and cardiovascular parameters like blood pressure (BP) in children is not well-established.
Purpose of the Study:
- To evaluate blood pressure (BP) differences in children diagnosed with idiopathic overactive bladder syndrome.
- To compare BP measurements between children with OAB and a healthy control group.
Main Methods:
- A case-control study involving 110 children with OAB (cases) and 220 healthy children (controls).
- Standard blood pressure measurements were taken for all participants.
- Statistical significance was determined using a P-value of <0.05.
Main Results:
- No significant difference in mean age between the OAB group (8.8 ± 1.70 years) and the control group (8.53 ± 2.44 years).
- A statistically significant difference in mean systolic and diastolic BP was observed between the groups (P = 0.001).
- Children with overactive bladder exhibited significantly higher systolic and diastolic blood pressure compared to controls.
Conclusions:
- Idiopathic overactive bladder syndrome in children is associated with elevated blood pressure.
- Further research is warranted to explore the underlying mechanisms connecting OAB and hypertension in pediatric populations.
- These findings suggest a potential link between bladder dysfunction and cardiovascular health in children.
Abstract:
Children with an overactive bladder generally exhibit frequency, urgency, and urge incontinence. Often, a child will squat to try to prevent urinary incontinence. The bladder in these children is not anatomically and is functionally, smaller than normal and exhibits strong uncontrolled contractions. The aim of this study was to the evaluation of blood pressure (BP) in children with idiopathic overactive bladder syndrome. In this case-control study, we selected 110 children with overactive bladder as cases and 220 children without overactive bladder as controls. Children with overactive bladder and healthy children without overactive bladder were enrolled, and their BP was measured in children. P <0.05 was considered statistically significant in our comparisons. The mean age of the children was 8.8 ± 1.70 and 8.53 ± 2.44 years in overactive bladder and control group, respectively. The mean systolic and diastolic BP were a significant difference between case and control groups (P = 0.001). Systolic and diastolic BP were significantly higher in children with overactive bladder.
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