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Updated: Feb 8, 2026

Isolating and Imaging Live, Intact Pacemaker Regions of Mouse Renal Pelvis by Vibratome Sectioning
Published on: April 30, 2021
A Pacemaker that was Avoided
Husnain Waseem1, Arsalan Talib Hashmi1, Maham Anser2
1Internal Medicine, Maimonides Medical Center, New York, USA.
Abstract:
Thyroxine is an essential hormone in the human body and exerts many effects on the cardiovascular system. The low metabolic state in hypothyroidism causes bradycardia and reduced cardiac contractility leading to reduced cardiac output. Severe bradycardia and atrioventricular (AV) blocks secondary to hypothyroidism have also been reported. We present a case of severe hypothyroidism causing a high-grade AV block which was successfully treated with thyroxine hormone replacement without requiring cardiac pacemaker placement.
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