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Development of Cell-Based Sentinels for Nitric Oxide: Ensuring Marker Expression and Unimodality

Ryan McKay1,2, Pricila Hauk1,2, David Quan1,2

  • 1Fischell Department of Bioengineering , University of Maryland , College Park , Maryland 20742 , United States.

ACS Synthetic Biology
|July 6, 2018
PubMed
Summary

Researchers engineered bacteria to detect nitric oxide (NO), a biomarker for Crohn's disease. These novel biosensors offer a potential non-invasive diagnostic tool, contrasting with traditional methods like colonoscopies.

Keywords:
biosensorinflammatory bowel diseaseprobioticssignal amplificationsynthetic biology

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