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Updated: Feb 8, 2026

Establishment of Epstein-Barr Virus Growth-transformed Lymphoblastoid Cell Lines
Published on: November 8, 2011
Epstein-Barr virus hepatitis can cause transient hepatopulmonary syndrome
Seiyed Mohammad Ali Ghayumi1, Maryam Rohani2, Sajad Hasanzadeh3
1Department of Internal Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Introduction:
Hepatopulmonary syndrome is commonly seen in the patients with chronic liver disease. Acute liver diseases are rarely associated with HPS. We have reported here a case of Transient HPS caused by Epstein-Barr virus hepatitis.
Case Report:
The patient was a 31 years old man that came to hospital due to RUQ pain and yellowish skin. In examination the patient was tachypnic and O2 saturation was 71% with prominent JVP. ver enzyme and bilirubin were high. All viral hepatitis was negative except anti viral capsid antigen-antibody of EBV. In Blood gas PaO2 was 54 mmHg, O2 saturation 73% and alveolar-arterial gradient was 18 mmHg. Stress Echocardiography with saline injection reported pulmonary arterial pressure 32 cmHg with delayed opacification of left atrium.
Conclusion:
transient HPS can be manifestation in the acute hepatitis caused by EBV infection.
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