Related Experiment Video
Updated: Feb 8, 2026
08:07
Paradigms of Lower Extremity Electrical Stimulation Training After Spinal Cord Injury
Published on: February 1, 2018
13.2K
Vibration-Assisted Home Training Program for Children With Spinal Muscular Atrophy
Christina Stark1,2, Ibrahim Duran3, Sebahattin Cirak4
1Children's and Adolescent's Hospital, University of Cologne, Cologne, Germany.
Child Neurology Open
|July 7, 2018
Summary
This study evaluated vibration-assisted rehabilitation for spinal muscular atrophy (SMA) types II and III. The program showed a significant improvement in functional mobility, but long-term benefits require further research.
Area of Science:
- Neuromuscular Rehabilitation
- Pediatric Physical Therapy
Background:
- Spinal muscular atrophy (SMA) types II and III impact motor function in children.
- Effective rehabilitation strategies are crucial for managing progressive neuromuscular disorders.
Purpose of the Study:
- To assess the efficacy of a novel vibration-assisted neuromuscular rehabilitation program for pediatric patients with SMA types II and III.
- To evaluate the impact of the 'Auf die Beine' program on motor abilities over a 12-month period.
Main Methods:
- Retrospective observational study of 38 children with SMA types II and III.
- A 6-month home-based program combining side-alternating whole-body vibration with intensive rehabilitation blocks.
- Motor function assessed using the Gross Motor Function Measure 66 (GMFM-66) and Hammersmith Functional Mobility Scale (HFMS) at baseline, 6 months, and 12 months.
Main Results:
- The Hammersmith Functional Mobility Scale demonstrated a statistically significant increase of 2.73 points (P = .007) after 12 months.
- The Gross Motor Function Measure showed a trend towards improvement with an increase of 1.69 points (P = .124).
- No significant adverse events were reported during the intervention.
Conclusions:
- Vibration-assisted neuromuscular rehabilitation may improve functional mobility in children with SMA types II and III.
- Further long-term studies are needed to confirm sustained clinical benefits and optimal application of this rehabilitation approach.
Related Concept Videos
01:18The Muscular System
7.2K
The muscular system is essential to the body's overall structure and function, playing a crucial role in movement, stability, and internal processes. It consists of three distinct types of muscle tissue: the skeletal, the smooth, and the cardiac muscles.
7.2K
01:19Vibrating Concrete
404
Mechanical vibrators are instrumental in compacting newly poured concrete within formwork and around reinforcements. This process is essential to eliminate trapped air pockets and establish a dense concrete mass. One widely used method is vibrating by internal vibrators, often referred to as a poker vibrator or immersion vibrator. It is rapidly inserted through the full depth of the freshly laid concrete and slightly extends into the layer below it (which remains in a plastic state). Consistent...
404
01:21Satellite Stem Cells and Muscular Dystrophy
2.4K
Satellite stem cells or myosatellite cells are quiescent stem cells that Alexander Mauro first identified in 1961. These cells are located between the sarcolemma, the plasma membrane of muscle fibers, and the basal lamina, the connective tissue sheath covering it. These mononucleated cells are activated in response to muscle injury, can transform into myoblasts, and may form or repair muscle fibers. Myosatellite cells can provide additional myonuclei for muscle regeneration or return to a...
2.4K
01:24IR Spectroscopy: Molecular Vibration Overview
4.8K
When Infrared (IR) radiation passes through a covalently bonded molecule, the bonds transition from lower to higher vibrational levels. The fundamental vibrational motions that result in infrared absorption can be classified as stretching or bending vibrations.
Stretching vibrations are vibrational motions that occur along the bond line, changing the bond length or distance between two bonded atoms. They are further distinguished as symmetric or asymmetric. In symmetric stretching, the...
Stretching vibrations are vibrational motions that occur along the bond line, changing the bond length or distance between two bonded atoms. They are further distinguished as symmetric or asymmetric. In symmetric stretching, the...
4.8K
01:29Drug Dosing: Infants and Children
309
Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
309
01:16IR Spectroscopy: Hooke's Law Approximation of Molecular Vibration
3.0K
A covalently bonded heteronuclear diatomic molecule can be modeled as two vibrating masses connected by a spring. The vibrational frequency of the bond can be expressed using an equation derived from Hooke's law, which describes how the force applied to stretch or compress a spring is proportional to the displacement of the spring. In this case, the atoms behave like masses, and the bond acts like a spring.
According to Hooke's law, the vibrational frequency is directly proportional to...
According to Hooke's law, the vibrational frequency is directly proportional to...
3.0K