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Related Concept Videos

What is Natural Selection?01:32

What is Natural Selection?

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Natural selection is an evolutionary process in which individuals with survival-promoting traits reproduce at higher rates. These favorable traits become more common within a population or species. Naturally selected traits initially arise via random genetic mutations. In order for selection to occur, there must be variation within a population, the trait controlling the variation must be heritable, and there must be an evolutionary advantage for variation in the trait.
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Many human characteristics, like height, are shaped by both nature—in other words, by our genes—and by nurture, or our environment. For example, chronic stress during childhood inhibits the production of growth hormones and consequently reduces bone growth and height. Scientists estimate that 70-90% of variation in height is due to genetic differences among individuals, and 10-30% of variation in height is due to differences in the environments that individuals experience,...
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Chirality is the most intriguing yet essential facet of nature, governing life’s biochemical processes and precision. It can be observed from a snail shell pattern in a macroscopic world to an amino acid, the minutest building block of life. Most of the snails around the world have right-coiled shells because of the intrinsic chirality in their genes. All the amino acids present in the human body exist in an enantiomerically pure state, except for glycine - the sole achiral amino acid.
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The nature of light has been a subject of inquiry since antiquity. In the seventeenth century, Isaac Newton performed experiments with lenses and prisms and was able to demonstrate that white light consists of the individual colors of the rainbow combined together. Newton explained his optics findings in terms of a "corpuscular" view of light, in which light was composed of streams of extremely tiny particles traveling at high speeds according to Newton's laws of motion.
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Related Experiment Video

Updated: Feb 8, 2026

Progressive-ratio Responding for Palatable High-fat and High-sugar Food in Mice
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[Research progress in natural allopyranosides].

Ying-ying Wang, Lei-yu Tian, Yan Yang

    Yao Xue Xue Bao = Acta Pharmaceutica Sinica
    |July 7, 2018
    PubMed
    Summary

    D-Allose, a rare sugar, offers unique benefits in drug development. Allopyranosides derived from it show promise for anti-tumor and anti-diabetic applications, enhancing drug efficacy and selectivity.

    Area of Science:

    • Natural Product Chemistry
    • Medicinal Chemistry
    • Pharmacology

    Background:

    • Glycosylation of natural products modifies stereochemistry, solubility, and pharmacokinetics.
    • D-Allose, a C-3 epimer of D-glucose, is rare but significant in food, health, and medicine.
    • Allopyranosides, natural conjugates, exhibit diverse biological activities.

    Purpose of the Study:

    • To review recent advancements in the phytochemistry and biological activity of allopyranosides.
    • To analyze structure-activity relationships of anti-tumor and anti-diabetic allopyranosides.
    • To provide insights for novel drug discovery and design using allopyranosides.

    Main Methods:

    • Literature review of phytochemistry and biological activity studies on allopyranosides.

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  • Analysis of structure-activity relationships based on reported data for anti-tumor and anti-diabetic allopyranosides.

    • Main Results:

    • Summary of progress in allopyranoside research, highlighting their unique properties.
    • Identification of key structural features influencing anti-tumor and anti-diabetic activities.
    • Demonstration of allopyranosides' potential for improved drug efficacy and selectivity.

    Conclusions:

    • Allopyranosides represent a promising class of compounds for therapeutic applications.
    • Structure-activity relationship insights guide the development of novel allopyranoside-based drugs.
    • Further research can leverage allopyranosides for new anti-cancer and anti-diabetic drug design.