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Evolving trends in bio/chemical sensor fabrication incorporating bimetallic nanoparticles
Riddhipratim Mandal1, Anupriya Baranwal1, Ananya Srivastava2
1Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati 781039, Assam, India.
Biosensors & Bioelectronics
|July 9, 2018
Summary
Composite metallic nanoparticles (MeNPs), particularly bimetallic nanoparticles (BNPs), offer enhanced properties for biosensor fabrication. This review details BNP synthesis, characterization, and applications in detecting various analytes, outperforming monometallic nanoparticles.
Area of Science:
- Nanotechnology and Materials Science
- Analytical Chemistry and Sensor Technology
Background:
- Nanotechnology integration has significantly advanced biosensor design, leveraging nanoscale materials' unique properties.
- Metallic nanoparticles (MeNPs), including gold and silver, have been widely used to enhance sensor performance.
- Research is shifting towards composite MeNPs, such as bimetallic nanoparticles (BNPs), for superior multifunctional properties over monometallic nanoparticles (mono-NPs).
Purpose of the Study:
- To provide insights into the synthesis of bimetallic nanoparticles (BNPs) for bio/chemical sensor fabrication.
- To review characterization techniques for investigating BNP properties and their complementary roles.
- To comprehensively report on the application of BNPs in fabricating sensors for diverse analytes.
Main Methods:
- Review of literature on bimetallic nanoparticle (BNP) synthesis strategies.
- Discussion of various characterization techniques (e.g., microscopy, spectroscopy) for BNP analysis.
- Compilation of data on BNP-based sensor fabrication and performance for specific analytes.
Main Results:
- Bimetallic nanoparticles (BNPs) exhibit advantageous multifunctional properties compared to monometallic nanoparticles (mono-NPs).
- Various synthesis routes enable the creation of BNPs with tailored characteristics for sensor applications.
- BNP-based biosensors demonstrate improved analytical performance (e.g., sensitivity, lower detection limits) for analytes like H2O2, glucose, and cells.
Conclusions:
- Bimetallic nanoparticles (BNPs) represent a significant advancement in biosensor technology, offering enhanced analytical capabilities.
- The strategic synthesis and characterization of BNPs are crucial for optimizing their performance in sensing matrices.
- BNPs are pivotal in developing next-generation biosensors with superior sensitivity and specificity for various applications.
Keywords:
Analytical performanceBimetallic nanoparticlesBio/chemical sensorsDiagnosticsMaterial engineeringMore Related Videos
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