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Retro-peritoneal paraganglioma, diagnosis and management
O Karray1, A Saadi1, M Chakroun1
1Urology department, Charles Nicolle hospital, Faculty of Medecine of Tunis, Tunis El Manar University, Tunis, Tunisia.
Summary
Retro-peritoneal paragangliomas are rare tumors. Surgical resection is the only curative treatment, with no recurrence observed in this study, highlighting the importance of peri-operative management.
Area of Science:
- Urology
- Surgical Oncology
- Endocrinology
Background:
- Paragangliomas are rare extra-adrenal tumors.
- Retro-peritoneal paragangliomas present symptoms similar to pheochromocytoma.
- Diagnosis requires hormonal assays and advanced imaging.
Observation:
- Five cases of retro-peritoneal paraganglioma were surgically treated between 2013 and 2017.
- Patients included 2 men and 3 women.
- Surgical approaches varied, including laparoscopic and open procedures.
Findings:
- Two patients had hypertension and palpitations, with elevated urinary hormones.
- One patient was asymptomatic, with incidental tumor discovery.
- Complete surgical resection led to symptom resolution and no recurrence during follow-up.
Implications:
- Complete surgical resection is the definitive curative treatment for retro-peritoneal paraganglioma.
- Peri-operative management of cardiovascular complications is crucial.
- Genetic evaluation may be indicated due to recurrence and associated neoplasm risks.
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