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Updated: Feb 8, 2026
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Author Spotlight: Establishing an Accurate Microhardness Testing Protocol for Craniofacial Tissues
Published on: April 26, 2024
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[Research progress on the relationship between oral microbes and digestive system diseases]
Bo-Lei Li1, Lei Cheng1, Xue-Dong Zhou1
1State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Conservative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Summary
Oral microbes impact digestive health, potentially causing diseases like colorectal cancer. This review explores the connection between oral bacteria and systemic digestive conditions.
Area of Science:
- Microbiology
- Gastroenterology
- Oral Health
Background:
- The human microbiome project has significantly advanced our understanding of oral microbes.
- Oral microbes are linked not only to oral diseases but also to systemic conditions.
- Emerging evidence connects oral microbiota to digestive system diseases, including colorectal cancer.
Purpose of the Study:
- To review recent studies on oral microbe-related digestive systemic diseases.
- To highlight the significant role of oral microbes in digestive health.
- To elucidate the pathways through which oral microbes affect digestive organs.
Main Methods:
- Literature review of recent studies.
- Analysis of research on oral microbiota and digestive diseases.
- Synthesis of findings on the oral-gut axis.
Main Results:
- Oral microbes play a considerable role in digestive systemic diseases.
- Specific oral bacteria are implicated in the origination and progression of digestive disorders.
- Mechanisms of oral microbe dissemination to the digestive system are being identified.
Conclusions:
- Oral microbes are crucial players in digestive systemic diseases.
- Understanding the oral-gut axis is vital for preventing and treating digestive conditions.
- Further research is needed to fully elucidate the impact of oral microbes on the digestive system.
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