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Updated: Feb 8, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Published on: June 12, 2021
Large Porcine Model of Profound Acute Ischemic Cardiogenic Shock
Ole K Møller-Helgestad1, Hanne B Ravn2, Jacob E Møller3
1Research Unit of Cardiology, Department of Cardiology, Odense University Hospital, Odense, Denmark. Ole.Moller-Helgestad@rsyd.dk.
Abstract:
Cardiogenic shock is one of the leading causes of death following acute myocardial infarction affecting 10% of patients with large myocardial infarcts with a subsequent mortality rate of 50%. Here we describe a large porcine model of acute ischemic cardiogenic shock. Acute left or right ventricular failure can be achieved with close to a 100% success rate by stepwise injection of microspheres into the left or right coronary artery, respectively, and the method allows for titration of heart failure to a prespecified level.
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