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Updated: Feb 8, 2026
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Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro
Published on: April 21, 2023
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Antimicrobial activity of the biogenically synthesized core-shell Cu@Pt nanoparticles
Renata Dobrucka1, Jolanta Dlugaszewska2
1Department of Industrial Products Quality and Ecology, Faculty of Commodity Science, Poznan University of Economics, al. Niepodległości 10, 61-875 Poznan, Poland.
Summary
Researchers synthesized bimetallic core-shell copper-platinum (Cu@Pt) nanoparticles using a plant extract. These novel nanoparticles show significant antibacterial and antifungal activity against various pathogens.
Area of Science:
- Nanotechnology and Materials Science
- Biotechnology and Green Chemistry
Background:
- Growing interest in biological synthesis of nanoparticles.
- Increasing focus on eco-friendly methods for bimetallic nanoparticle production.
Purpose of the Study:
- To synthesize bimetallic core-shell copper-platinum (Cu@Pt) nanoparticles using a biological approach.
- To characterize the synthesized Cu@Pt nanoparticles.
- To evaluate the antimicrobial efficacy of the Cu@Pt nanoparticles.
Main Methods:
- Biological synthesis utilizing *Agrimoniae herba* extract.
- Characterization using UV-vis, FT-IR, SEM, TEM, and AFM.
- Antimicrobial activity testing against bacteria, yeast, and dermatophytes.
Main Results:
- Successful synthesis of core-shell Cu@Pt nanoparticles confirmed by various microscopy and spectroscopy techniques.
- Demonstrated significant antibacterial activity against Gram-negative bacteria (*E. coli*, *P. aeruginosa*) and Gram-positive bacteria (*S. aureus*).
- Exhibited antifungal activity against yeast (*C. albicans*) and dermatophytes (*T. mentagrophytes*).
Conclusions:
- The plant extract provides an effective green route for synthesizing bimetallic Cu@Pt nanoparticles.
- The synthesized core-shell Cu@Pt nanoparticles possess broad-spectrum antimicrobial properties.
- Potential applications in antimicrobial formulations and treatments.
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