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Advances in Selective Carbon-Heteroatom Coupling Reactions
Qingle Zeng1, Li Zhang1, Yue Zhou1
1State Key Laboratory of Geohazard Prevention and Geoenvironment Protection (Chengdu University of Technology), Chengdu University of Technology, College of Materials, Chemistry & Chemical Engineering, 1#, Dongsanlu, Erxianqiao, Chengdu, 610059, China.
Selective carbon-heteroatom coupling reactions offer efficient synthesis by minimizing byproducts. This review highlights recent advances in C-N, C-O, and C-C coupling, inspiring future research in synthetic chemistry.
Area of Science:
- Organic Chemistry
- Synthetic Chemistry
Background:
- Compounds with multiple reactive groups often yield byproducts during coupling.
- Selective carbon-heteroatom coupling reactions enhance synthetic efficiency and atom economy.
Purpose of the Study:
- To review recent advancements in selective carbon-heteroatom coupling reactions.
- To inspire future research directions in this field.
Main Methods:
- Literature review of selective coupling reactions.
- Categorization based on reaction types: C-N/C-N, C-N/C-O, C-O/C-O, C-C/C-N.
Main Results:
- Significant progress has been made in various selective coupling reactions.
- The review covers diverse reaction pathways and their efficiencies.
Conclusions:
- Selective carbon-heteroatom coupling is crucial for efficient synthesis.
- Further exploration is needed to fully realize the potential of these reactions.
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