Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Single Nucleotide Polymorphisms-SNPs01:05

Single Nucleotide Polymorphisms-SNPs

18.4K
A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
18.4K
The Evidence for Evolution02:55

The Evidence for Evolution

48.3K
Genetic variations accumulating within populations over generations give rise to biological evolution. Evolutionary changes can result in the formation of novel varieties and entire new species. These changes are responsible for the diverse forms of life inhabiting the planet. The evidence for evolution suggests that all living organisms descended from common ancestors.
48.3K
Convergent Evolution01:54

Convergent Evolution

33.0K
Evolution shapes the features of organisms over time, ensuring that they are suited for the environments in which they live. Sometimes, selection pressure leads to the rise of similar but unrelated adaptations in organisms with no recent common ancestors, a process known as convergent evolution.
33.0K
Dialysis01:27

Dialysis

1.5K
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
1.5K
Dialysis01:15

Dialysis

1.8K
Dialysis is a diffusion-based purification process that separates analyte molecules from a complex matrix. This is accomplished by allowing molecules in the solution to pass through a semipermeable membrane into a liquid on the other side. The membrane is usually made of cellulose acetate or cellulose nitrate, and the second liquid must be miscible with the solution. Ions (e.g., chloride or sodium) or organic molecules (e.g., glucose) can pass through the membrane pores, which generally have...
1.8K
Nucleotide Excision Repair01:08

Nucleotide Excision Repair

40.9K
Overview
40.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Genome-wide association and MaODR-based multi-locus interaction analyses reveal a susceptibility gene network for newly identified metabolic syndrome.

Genome biology·2026
Same author

Nomogram Development for Predicting Synchronous Lung Metastasis in Patients with T1 Colorectal Cancer: An SEER-Based Analysis.

Medicina (Kaunas, Lithuania)·2026
Same author

Machine Learning for Establishing the Precision Prediction of Sarcopenia.

Gerontology·2026
Same author

Application of a novel approach for dementia prevalence prediction in Taiwan.

Scientific reports·2026
Same author

AI-Driven Fall Prediction across Generations: Integrating Deep Learning and Machine Learning for Young, Middle-Aged, and Older Adults.

Gerontology·2025
Same author

Long non-coding RNA C20orf56 as a predictor of response to neoadjuvant CCRT and survival rates of rectal cancers.

Histology and histopathology·2025
Same journal

Investigating Effect of Dimensional Variance on Separation of Glomerular Ultrafiltrate in a Microfluidic Environment.

IEEE transactions on nanobioscience·2026
Same journal

Green synthesis of multifunctional ZnFe<sub>2</sub>O<sub>4</sub>-MWCNT-Cellulose acetate nanocomposite for peroxidase enzyme immobilization.

IEEE transactions on nanobioscience·2026
Same journal

IoT-Enabled SnOâ‚‚-Based Humidity Sensor for Real-Time Monitoring in Neonatal Incubators.

IEEE transactions on nanobioscience·2026
Same journal

Electrokinetic and Antibiofilm Effects of Silver Nanoparticles Combined with Imipenem Against multidrug-resistant of Klebsiella pneumoniae.

IEEE transactions on nanobioscience·2026
Same journal

Bio-inspired Optofluidic Molecular Communication with Photothermally Actuated Microrobot Swarms.

IEEE transactions on nanobioscience·2026
Same journal

Nanostructured ZnO Thin Film-Based Enzymatic Biosensor for Sensitive Acetylcholine Detection in Neurological Applications.

IEEE transactions on nanobioscience·2026
See all related articles

Related Experiment Video

Updated: Feb 8, 2026

Genotyping Single Nucleotide Polymorphisms in the Mitochondrial Genome by Pyrosequencing
07:24

Genotyping Single Nucleotide Polymorphisms in the Mitochondrial Genome by Pyrosequencing

Published on: February 10, 2023

2.0K

Catfish Taguchi-Based Binary Differential Evolution Algorithm for Analyzing Single Nucleotide Polymorphism

Cheng-Hong Yang, Yi-Kai Kao, Li-Yeh Chuang

    IEEE Transactions on Nanobioscience
    |July 12, 2018
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces a novel Catfish Taguchi-based Binary Differential Evolution (CT-BDE) algorithm to efficiently identify complex single-nucleotide polymorphism (SNP)-SNP interactions in genetic association studies.

    More Related Videos

    Author Spotlight: Genetic Profiling for Fluorouracil Response in Gastric Cancer
    06:21

    Author Spotlight: Genetic Profiling for Fluorouracil Response in Gastric Cancer

    Published on: May 10, 2024

    1.3K
    The Visual Colorimetric Detection of Multi-nucleotide Polymorphisms on a Pneumatic Droplet Manipulation Platform
    10:01

    The Visual Colorimetric Detection of Multi-nucleotide Polymorphisms on a Pneumatic Droplet Manipulation Platform

    Published on: September 27, 2016

    8.0K

    Related Experiment Videos

    Last Updated: Feb 8, 2026

    Genotyping Single Nucleotide Polymorphisms in the Mitochondrial Genome by Pyrosequencing
    07:24

    Genotyping Single Nucleotide Polymorphisms in the Mitochondrial Genome by Pyrosequencing

    Published on: February 10, 2023

    2.0K
    Author Spotlight: Genetic Profiling for Fluorouracil Response in Gastric Cancer
    06:21

    Author Spotlight: Genetic Profiling for Fluorouracil Response in Gastric Cancer

    Published on: May 10, 2024

    1.3K
    The Visual Colorimetric Detection of Multi-nucleotide Polymorphisms on a Pneumatic Droplet Manipulation Platform
    10:01

    The Visual Colorimetric Detection of Multi-nucleotide Polymorphisms on a Pneumatic Droplet Manipulation Platform

    Published on: September 27, 2016

    8.0K

    Area of Science:

    • Genetics and Bioinformatics
    • Computational Biology
    • Statistical Genetics

    Background:

    • Single-nucleotide polymorphism (SNP)-SNP interactions are critical for understanding multifactorial diseases.
    • Current statistical methods struggle with the computational demands of identifying these complex interactions.
    • Identifying SNP-SNP interactions remains a significant challenge in genetic association studies.

    Purpose of the Study:

    • To propose a novel algorithm, the Catfish Taguchi-based Binary Differential Evolution (CT-BDE), for identifying SNP-SNP interactions.
    • To enhance the efficiency and accuracy of detecting high-order SNP-SNP interactions.
    • To evaluate the performance of the proposed algorithm against existing methods.

    Main Methods:

    • Development of the Catfish Taguchi-based Binary Differential Evolution (CT-BDE) algorithm.
    • Incorporation of the 'catfish effect' to prevent premature population convergence.
    • Integration of the Taguchi method to improve search capabilities.
    • Utilization of a fitness function derived from Multifactor Dimensionality Reduction (MDR) for solution evaluation.

    Main Results:

    • The CT-BDE algorithm demonstrated superior performance in identifying SNP-SNP interactions compared to other BDE-based algorithms.
    • The proposed algorithm effectively identified high-order SNP-SNP interactions.
    • The MDR-derived fitness function proved more effective than case-control difference for evaluating solutions.

    Conclusions:

    • The CT-BDE algorithm offers a powerful and efficient approach for identifying complex SNP-SNP interactions.
    • This method advances the analysis of genetic association studies for multifactorial diseases.
    • The CT-BDE algorithm with an MDR-derived fitness function represents a significant improvement in the field.