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Updated: Feb 7, 2026

Using Cholesky Decomposition to Explore Individual Differences in Longitudinal Relations between Reading Skills
Published on: September 17, 2019
Hallmarks of Cancer in the Reading Room: A Guide for Radiologists
Ailbhe C O'Neill1,2,3, Francesco Alessandrino2,3, Sree Harsha Tirumani2,3
11 Department of Radiology, St Vincent's University Hospital, Elm Park, Dublin, Ireland.
Objective:
The hallmarks of cancer are mechanisms that cells develop to undergo malignant transformation. The targeting of these hallmarks by newer cancer therapies results in new mechanisms of response, toxicity, and resistance. The purpose of this article is to review these hallmarks, their associated targeted therapies, imaging features of responses, and toxicities.
Conclusion:
Ten hallmarks, among them proliferative signaling, angiogenesis, immune response, and genome instability, are reviewed. Molecular targeted therapies, including antiangiogenic factors and immune checkpoint inhibitors, target these hallmarks.
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