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Updated: Feb 7, 2026

Anticancer Efficacy of Photodynamic Therapy with Lung Cancer-Targeted Nanoparticles
Published on: December 1, 2016
Recent Progress in Metal-Based Nanoparticles Mediated Photodynamic Therapy
Jingyao Sun1,2, Semen Kormakov3, Ying Liu4
1College of Mechanical and Electrical Engineering, Beijing University of Chemical Technology, Beijing 100029, China. sunjingyao5566@sina.com.
Abstract:
Photodynamic therapy (PDT) is able to non-invasively treat and diagnose various cancers and nonmalignant diseases by combining light, oxygen, and photosensitizers (PSs). However, the application of PDT is hindered by poor water solubility and limited light-penetration depth of the currently available photosensitizers (PSs). Water solubility of PSs is crucial for designing pharmaceutical formulation and administration routes. Wavelength of light source at visible range normally has therapeutic depth less than 1 mm. In this review, focus is on the recent research progress of metal-based nanoparticles being applied in PDT. The potential toxicity of these nanoscales and future directions are further discussed.
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