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Updated: Feb 7, 2026

Thermal Ablation for the Treatment of Abdominal Tumors
Published on: March 7, 2011
Radiofrequency ablation of small renal masses in comorbid patients
Jerzy Siekiera1, Milosz Jasinski1, Witold Mikołajczak2
1Department of Oncological Urology, Oncology Centre, Bydgoszcz, Poland.
Introduction:
Over the recent years, the progress in imaging techniques has led to increased detection of small renal masses (SRMs), including in elderly and high-risk patients. Partial nephrectomy (nephron-sparing surgery - NSS), the current standard of care in T1a kidney tumours, has some limitations in patients who are poor candidates for surgery, as it is associated with potential perioperative complications and possible renal function loss. Radiofrequency ablation (RFA), a minimally invasive method that can be performed percutaneously, is an option in such cases.
Aim:
To present our experience in treatment of SRMs using RFA in comorbid patients.
Material And Methods:
In the years 2006-2012, 103 percutaneous, ultrasound-guided RFA procedures were performed in the Oncology Centre in Bydgoszcz in patients with an ASA score ≥ 3. Abdominal computed tomography and tumour biopsy were performed before the procedure. The average follow-up time was 46 months.
Results:
The 1, 3 and 5-year overall survival rates were respectively 97%, 90% and 75%, while cancer-specific survival was 100%. No Clavien-Dindo grade ≥ 3 complications were observed.
Conclusions:
Radiofrequency ablation performed percutaneously is a minimally invasive treatment and may be applied in patients who are, due to comorbidities, poor candidates for surgery. In comorbid patients, where other causes of death play an important role, the application of a minimally invasive treatment method with satisfactory oncological effectiveness is justified.
Insights
Radiofrequency ablation (RFA) offers a minimally invasive treatment option for small renal masses (SRMs) in high-risk patients. This study shows RFA is a safe and effective approach with excellent survival rates and minimal complications.
Area of Science:
- Urology
- Oncology
- Minimally Invasive Surgery
Background:
- Increasing detection of small renal masses (SRMs) due to advanced imaging.
- Partial nephrectomy (NSS) is standard for T1a tumors but has limitations for high-risk patients.
- Radiofrequency ablation (RFA) presents a minimally invasive alternative for patients unsuitable for surgery.
Purpose of the Study:
- To evaluate the experience with radiofrequency ablation (RFA) for treating small renal masses (SRMs) in comorbid patients.
- To assess the safety and efficacy of RFA in a high-risk surgical population.
Main Methods:
- 103 percutaneous, ultrasound-guided RFA procedures were performed between 2006-2012.
- Patients had an American Society of Anesthesiologists (ASA) score ≥ 3.
- Procedures included pre-procedural CT scans and tumor biopsies, with an average follow-up of 46 months.
Main Results:
- 1, 3, and 5-year overall survival rates were 97%, 90%, and 75%, respectively.
- Cancer-specific survival was 100%.
- No major complications (Clavien-Dindo grade ≥ 3) were observed.
Conclusions:
- Percutaneous RFA is a safe and effective minimally invasive treatment for SRMs in comorbid patients.
- RFA is a viable option for patients who are poor surgical candidates due to comorbidities.
- The oncological effectiveness of RFA justifies its use in comorbid patients where other mortality causes are significant.
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