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Related Concept Videos

Adhesion01:14

Adhesion

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Adhesion occurs when one type of molecule is attracted to a different molecule. Water exhibits adhesive properties in the presence of polar surfaces, such as glass or cellulose in plants. For instance, when water is poured into a glass, the positively charged hydrogen molecules of water are more attracted to the negatively charged oxygen molecules in the silica than to the oxygen in neighboring water molecules.
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Cell Adhesion in Plants01:14

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Plants have rigid cell walls that are made up of cell wall polysaccharides that mediate cell-cell adhesion. The primary cell walls of plants consist of two independent and interacting polysaccharide networks: a pectin matrix that embeds the second network comprising cellulose and hemicelluloses.
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Immunoglobulin-like Cell Adhesion Molecules01:31

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Immunoglobulin-like cell adhesion molecules or Ig-CAMs are a versatile group of cell surface glycoproteins belonging to the immunoglobulin protein superfamily. Ig-CAMs possess the characteristic immunoglobulin protein domains and other domains such as the fibronectin type III domain. The Ig domains are glycosylated to varying degrees in different Ig-CAMs.
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Cell Adhesion Molecules - Types and Functions01:20

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Cell adhesion molecules (CAMs) are pivotal to multicellularity and the coordinated functioning of tissues and organ systems. They enable physical interactions between cells and provide mechanical strength to tissues. They also function as receptors for signal transmission across the plasma membrane. The CAMs are broadly classified into four families - integrins, cadherins, selectins, and immunoglobulin-like CAMs (IgCAMs).
CAM Families
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Bacterial Transformation01:33

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In 1928, bacteriologist Frederick Griffith worked on a vaccine for pneumonia, which is caused by Streptococcus pneumoniae bacteria. Griffith studied two pneumonia strains in mice: one pathogenic and one non-pathogenic. Only the pathogenic strain killed host mice.
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Bacterial Signaling01:30

Bacterial Signaling

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Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
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Related Experiment Video

Updated: Feb 7, 2026

Bacterial Cell Culture at the Single-cell Level Inside Giant Vesicles
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Bacterial Cell Culture at the Single-cell Level Inside Giant Vesicles

Published on: April 30, 2019

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Bacterial adhesion at the single-cell level.

Cecile Berne1, Courtney K Ellison1, Adrien Ducret2

  • 1Department of Biology, Indiana University, Bloomington, IN, USA.

Nature Reviews. Microbiology
|July 17, 2018
PubMed
Summary
This summary is machine-generated.

Bacterial biofilms form when planktonic cells adhere to surfaces. This review details the single-cell mechanisms driving reversible and irreversible bacterial adhesion, crucial for biofilm development.

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Related Experiment Videos

Last Updated: Feb 7, 2026

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In Vitro Assay of Bacterial Adhesion onto Mammalian Epithelial Cells
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Area of Science:

  • Microbiology
  • Biophysics

Background:

  • Biofilm formation begins with planktonic cell adhesion to surfaces.
  • This transition involves complex biological, chemical, and physical factors.
  • Initial reversible adhesion strengthens to irreversible attachment.

Purpose of the Study:

  • To review mechanisms of bacterial adhesion at the single-cell level.
  • To elucidate forces governing cell-surface interactions.
  • To understand the transition from reversible to irreversible adhesion.

Main Methods:

  • Review of existing literature on bacterial adhesion.
  • Analysis of physical forces in cell-surface interactions.
  • Examination of single-cell adhesion dynamics.

Main Results:

  • Bacterial adhesion is governed by surface properties, environmental conditions, and cell characteristics.
  • Physical forces play a critical role in initial contact and adhesion strengthening.
  • The transition from reversible to irreversible adhesion is a key step in biofilm formation.

Conclusions:

  • Understanding single-cell adhesion mechanisms is vital for controlling biofilm formation.
  • Further research into the biophysics of bacterial adhesion can inform strategies against biofilms.