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Updated: Feb 7, 2026

Operation of the Collaborative Composite Manufacturing CCM System
Published on: October 1, 2019
An Industry-Driven Roadmap for Manufacturing in Regenerative Medicine
Joshua G Hunsberger1, Thomas Shupe1, Anthony Atala1
1Wake Forest Institute for Regenerative Medicine, Wake Forest University, Winston-Salem, North Carolina, USA.
Abstract:
Regenerative medicine is poised to become a significant industry within the medical field. As such, the development of strategies and technologies for standardized and automated regenerative medicine clinical manufacturing has become a priority. An industry-driven roadmap toward industrial scale clinical manufacturing was developed over a 3-year period by a consortium of companies with significant investment in the field of regenerative medicine. Additionally, this same group identified critical roadblocks that stand in the way of advanced, large-scale regenerative medicine clinical manufacturing. This perspective article details efforts to reach a consensus among industry stakeholders on the shortest pathway for providing access to regenerative medicine therapies for those in need, both within the United States and around the world. Stem Cells Translational Medicine 2018;7:564-568.
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