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Preparation of Keratin Hydrolysate from Chicken Feathers and Its Application in Cosmetics
Published on: November 27, 2017
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Immunomodulatory Protein Hydrolysates and Their Application.
Mensiena B G Kiewiet1, Marijke M Faas2, Paul de Vos3
1Immunoendocrinology, Division of Medical Biology, Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands. m.b.g.kiewiet@umcg.nl.
Nutrients
|July 18, 2018
Summary
Consuming immunomodulatory protein hydrolysates may prevent immune-related diseases. Identifying specific protein sequences and understanding their mechanisms are key to developing effective hydrolysates for health and nutrition.
Area of Science:
- Food Science and Immunology
- Biochemistry
- Nutrition Science
Background:
- Western lifestyle diseases are increasingly linked to immune dysfunction.
- Protein hydrolysates show potential for modulating immune responses.
- Understanding the active components and mechanisms of protein hydrolysates is crucial for targeted development.
Purpose of the Study:
- To review the immunomodulatory effects of protein hydrolysates in vivo.
- To explore the mechanisms underlying these immune effects.
- To discuss applications and methods for identifying bioactive protein sequences.
Main Methods:
- Literature review of in vivo studies on protein hydrolysates and immune effects.
- Analysis of current research on the mechanisms of immunomodulation.
- Discussion of physicochemical approaches for identifying immune-active protein sequences.
Main Results:
- Protein hydrolysates demonstrate specific immunomodulatory effects in both intestinal and systemic organs.
- Advances have been made in identifying the components responsible for these immune effects.
- Knowledge of underlying mechanisms is expanding.
Conclusions:
- Specific compositions of protein hydrolysates elicit distinct immune effects.
- This knowledge can enhance products like sports nutrition, clinical nutrition, and infant formula.
- Immunomodulatory protein hydrolysates offer potential for managing immune dysfunction in aging or stressed populations.
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