Related Experiment Video
Updated: Feb 7, 2026

Author Spotlight: Enhancing Candida albicans Detection in Catheter Infections Using Fluorescent Protein Tagging
Published on: March 22, 2024
Establishing catheter-related bloodstream infection surveillance to drive improvement
Carole Hallam1, Tim Jackson1, Anu Rajgopal1
1Calderdale and Huddersfield NHS Foundation Trust, Lindley, Huddersfield, UK.
Insights
Implementing a surveillance program significantly reduced catheter-related bloodstream infections (CRBSI) in a hospital trust. This initiative monitored CRBSI rates and demonstrated the success of quality improvement efforts.
Area of Science:
- Healthcare Quality Improvement
- Infection Prevention and Control
- Medical Surveillance
Background:
- Catheter-related bloodstream infections (CRBSI) are a significant complication of central venous access devices.
- CRBSI are often poorly measured, hindering effective management.
- This study details a hospital trust's process for establishing CRBSI surveillance and reduction strategies.
Purpose of the Study:
- To establish a comprehensive surveillance process for CRBSI across all hospital specialties.
- To implement a quality improvement program aimed at reducing CRBSI rates.
- To effectively measure the impact of interventions on CRBSI incidence.
Main Methods:
- Development and application of locally adapted CRBSI criteria.
- Utilization of root cause analysis (RCA) for investigating CRBSI cases.
- Implementation of a multi-specialty surveillance program over five years.
Main Results:
- A significant and sustained reduction in CRBSI rates was observed.
- CRBSI incidence decreased from 5 to 0.23 per 1000 catheter days.
- The surveillance system successfully monitored CRBSI trends throughout the trust.
Conclusions:
- The established surveillance system enabled effective monitoring of CRBSI rates.
- The quality improvement initiatives led to a measurable and substantial reduction in CRBSI.
- This approach provides a model for other institutions seeking to reduce CRBSI.
Background:
Catheter-related blood stream infections (CRBSI) are an important complication of central venous access devices but are often poorly measured. This article describes the journey of one hospital trust to set up a surveillance process for CRBSI across all specialties of the trust and to reduce CRBSI.
Method:
Using a locally adapted CRBSI criteria and root cause analysis (RCA) for investigation we identified a number of opportunities for a quality improvement programme.
Findings:
Over a 5-year period we saw a significant and sustained reduction in the rate of CRBSI from 5 per 1000 catheter days to 0.23 per 1000 catheter days.
Conclusions:
The surveillance enabled rates of CRBSI to be monitored across the trust and the success of our improvements to be measured.
Related Concept Videos
Principles of Disease Surveillance
Energy to Drive Translocation
Generally, polypeptides are unfolded by two distinct...
Immune Surveillance by NK Cells and Phagocytes
Natural Killer Cells: The Fast Responders
NK cells are large granular lymphocytes found in the blood and lymphatic system. These...
M-Cdk Drives Transition Into Mitosis
Cyclin-dependent kinases, or Cdks, work in concert with cyclins to control cell cycle transitions. M-Cdk, a complex of Cdk1 bound to M cyclin, is a well-known example of this coordinated control that drives the transition from the G2 to the M phase.
M cyclin...
Drive-Reduction Theory: Push Theory of Motivation
Improving Translational Accuracy

