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Updated: Feb 7, 2026

Molten-Salt Synthesis of Complex Metal Oxide Nanoparticles
Published on: October 27, 2018
Metal-free formal synthesis of phenoxazine
Gabriella Kervefors1, Antonia Becker1, Chandan Dey1
1Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, SE-106-91 Stockholm, Sweden.
Abstract:
A transition metal-free formal synthesis of phenoxazine is presented. The key step of the sequence is a high-yielding O-arylation of a phenol with an unsymmetrical diaryliodonium salt to provide an ortho-disubstituted diaryl ether. This species was cyclized to acetylphenoxazine in moderate yield. The overall yield in the three-step sequence is 72% based on recovered diaryl ether. An interesting, unusually stable iodine(III) intermediate in the O-arylation was observed by NMR and could be converted to the product upon longer reaction time.
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