Anthropometry and Malaria among Children in Niger: A Cross-Sectional Study

Kieran S O'Brien1, Abdou Amza2, Boubacar Kadri2

  • 1Francis I. Proctor Foundation, University of California San Francisco, San Francisco, California.

Insights

This study found no strong link between malnutrition indicators and malaria infection in young children in Niger. However, greater height may be associated with a higher risk of clinical malaria.

Area of Science:

  • Global Health
  • Pediatric Infectious Diseases
  • Nutritional Epidemiology

Background:

  • Malnutrition and malaria disproportionately affect children under 5 in sub-Saharan Africa, often co-occurring seasonally.
  • Previous research on the malnutrition-malaria relationship in children has yielded inconclusive results.
  • Understanding this complex interaction is crucial for public health interventions.

Purpose of the Study:

  • To investigate the association between anthropometric indicators of malnutrition and malaria infection in children under 5 years old in Niger.
  • To analyze the relationship between height-for-age z-score (HAZ) and weight-for-age z-score (WAZ) with malaria parasitemia and clinical malaria.

Main Methods:

  • Secondary analysis of a cluster-randomized trial on trachoma treatment in Niger.
  • Cross-sectional study including 1,649 children aged 6-60 months with anthropometric and malaria data.
  • Statistical models evaluated associations between HAZ/WAZ and malaria parasitemia/clinical malaria.

Main Results:

  • 47.3% of children had malaria parasitemia and 24.3% had clinical malaria.
  • No significant association was found between height-for-age z-score (HAZ) or weight-for-age z-score (WAZ) and malaria parasitemia.
  • A potential association was observed between greater height and an increased risk of clinical malaria.

Conclusions:

  • Most anthropometric indicators were not significantly associated with malaria infection in this population.
  • Height-for-age z-score showed a marginal association with increased risk of clinical malaria.
  • Further research is needed to clarify the nuanced relationship between nutritional status and malaria risk in children.

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