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Microfluidic viscometry using magnetically actuated micropost arrays.

Robert M Judith1, Bethany Lanham1, Michael R Falvo1

  • 1Dept. of Physics & Astronomy, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.

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|July 18, 2018
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Summary
This summary is machine-generated.

This study introduces a novel microfluidic viscometer using magnetic micro-posts for precise viscosity measurements of small fluid samples. The developed analytical model accurately predicts fluid dynamics and guides the design of advanced microviscometry systems.

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Area of Science:

  • Microfluidics
  • Biophysics
  • Materials Science

Background:

  • Viscometry traditionally requires larger sample volumes.
  • Existing microfluidic methods may lack quantitative accuracy or broad applicability.
  • Flexible microactuators offer potential for novel sensing modalities.

Purpose of the Study:

  • To develop a microfluidic viscometer capable of quantitative viscosity measurements.
  • To demonstrate the efficacy of magnetically actuated micro-post arrays for viscometry.
  • To create a comprehensive analytical model for predicting microactuator dynamics in fluids.

Main Methods:

  • Development of a microfluidic device with arrays of magnetically actuated micro-posts.
  • Quantitative viscosity measurements using <20 μL sample volumes.
  • Creation and application of a comprehensive analytical model incorporating mechanical, magnetic, optical, and fluid-structure interaction properties.

Main Results:

  • Achieved quantitative viscosity measurements over three orders of magnitude.
  • Demonstrated the first use of driven flexible micropost arrays for quantitative viscometry.
  • Validated the analytical model, highlighting the importance of the 'sperm number' for accurate fluid property determination.

Conclusions:

  • The developed microfluidic viscometer offers a sensitive and accurate method for fluid characterization.
  • The analytical model is broadly applicable to various flexible microactuator designs.
  • The model can guide the optimization of microactuator arrays for expanded measurement ranges.