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[Relevance of fluoroquinolones prescriptions in medical service]

C Lo Presti1, A Blaise2, M Maestracci1

  • 1Service pharmacie, centre hospitalier de Salon-de-Provence, 13300 Salon-de-Provence, France.

Revue De Pneumologie Clinique
|July 19, 2018
PubMed
Abstract

Insights

Fluoroquinolone (FQ) antibiotic prescriptions in a French hospital were assessed, revealing only 38% were justified. Improving FQ prescribing practices is crucial to combat antibiotic resistance.

Area of Science:

  • Infectious Diseases
  • Pharmacology
  • Hospital Pharmacy

Background:

  • Fluoroquinolones (FQ) are widely used antibiotics associated with resistance.
  • A 2015 French guideline aimed to preserve FQ utility.
  • High FQ consumption in a hospital pneumology service prompted an assessment.

Purpose of the Study:

  • To evaluate the appropriateness of fluoroquinolone prescriptions.
  • To identify areas for improvement in FQ prescribing practices.

Main Methods:

  • Retrospective study of FQ prescriptions from January 1 to December 31, 2015.
  • Analysis of prescription justification, bacteriological documentation, and reassessment rates.

Main Results:

  • Only 38% of FQ prescriptions were justified; 25% were unjustified, primarily for lung infections.
  • Bacteriological documentation was present in only 35% of cases.
  • 53% of prescriptions were reassessed within 48-72 hours, with non-conformities noted in 22% of justified prescriptions.

Conclusions:

  • Significant improvements are needed in FQ prescription relevance.
  • Disseminating findings and implementing corrective actions can enhance FQ prescribing.
  • Optimizing FQ use is essential for antimicrobial stewardship.
Keywords:
AntibiothérapieAntibioticsFluoroquinolonesIndicationPertinencePneumologie, IndicationPneumologyRelevance

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