Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Factors Affecting Renal Clearance: Drug's Physicochemical Properties and Plasma Levels01:31

Factors Affecting Renal Clearance: Drug's Physicochemical Properties and Plasma Levels

604
Renal clearance of a drug is influenced by various factors, including its physicochemical properties and plasma levels. These factors play a significant role in determining how efficiently the kidneys eliminate a drug.
One important factor is the drug's molecular size. The kidneys readily excrete smaller molecules below 300 Daltons (Da). On the other hand, molecules weighing between 300 and 500 Da are excreted through both urine and bile. Larger molecules above 500 Da tend to be excreted...
604
Decision Making01:20

Decision Making

994
Decision-making is a fundamental cognitive process that involves evaluating alternatives and selecting among them. This process can range from simple choices, such as deciding what to wear, to complex decisions, like choosing a major in college or a career path. The complexity of the decision often dictates the approach we use, which can be broadly categorized into two types: automatic and controlled decision-making.
Automatic decision-making is fast, intuitive, and relies on gut feelings...
994
Aging01:26

Aging

714
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
714
Decision Making: P-value Method01:09

Decision Making: P-value Method

7.0K
The process of hypothesis testing based on the P-value method includes calculating the P- value using the sample data and interpreting it.
First, a specific claim about the population parameter is proposed. The claim is based on the research question and is stated in a simple form. Further, an opposing statement to the claim  is also stated. These statements can act as null and alternative hypotheses:  a null hypothesis would be a neutral statement while the alternative hypothesis can...
7.0K
Neural Regulation01:37

Neural Regulation

43.4K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
43.4K
Leveling Effect01:29

Leveling Effect

1.4K
In acid-base chemistry, the leveling effect refers to the limitation imposed by the solvent on the strength of acids and bases in solution. When a base stronger than the solvent's conjugate base is used, it deprotonates the solvent until the base is entirely consumed, making it ineffective against weaker acids. Conversely, an acid stronger than the solvent's conjugate acid protonates the solvent until the acid is depleted, rendering it ineffective against weaker bases. Essentially, the...
1.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hierarchical Coarse-to-Fine cGAN for Subtype-Specific Freezing of Gait Signal Generation.

IEEE journal of biomedical and health informatics·2026
Same author

Moving intentions from brains to machines.

Trends in cognitive sciences·2026
Same author

The efficacy and feasibility of an immersive virtual reality game to train spatial attention orientation after stroke: A stage 2 report.

Journal of neuropsychology·2024
Same author

Bistable Perception Discriminates Between Depressive Patients, Controls, Schizophrenia Patients, and Their Siblings.

Schizophrenia bulletin·2024
Same author

Gaze-contingent processing improves mobility, scene recognition and visual search in simulated head-steered prosthetic vision.

Journal of neural engineering·2024
Same author

Towards biologically plausible phosphene simulation for the differentiable optimization of visual cortical prostheses.

eLife·2024

Related Experiment Video

Updated: Feb 7, 2026

Integrating Visual Psychophysical Assays within a Y-Maze to Isolate the Role that Visual Features Play in Navigational Decisions
07:09

Integrating Visual Psychophysical Assays within a Y-Maze to Isolate the Role that Visual Features Play in Navigational Decisions

Published on: May 2, 2019

6.5K

Changes in low-level neural properties underlie age-dependent visual decision making.

Elahe Arani1, Raymond van Ee2,3,4, Richard van Wezel2,5

  • 1Biophysics Department, Donders Institute for Brain, Cognition and Behaviour, Radboud University, 6525AJ, Nijmegen, The Netherlands. E.arani@donders.ru.nl.

Scientific Reports
|July 19, 2018
PubMed
Summary

Aging affects visual perceptual decisions, particularly the variability in percept durations and alternation rates. Changes in neural adaptation and noise, not inhibition, underlie these age-related cognitive declines.

More Related Videos

Studying Age-dependent Genomic Instability using the S. cerevisiae Chronological Lifespan Model
08:46

Studying Age-dependent Genomic Instability using the S. cerevisiae Chronological Lifespan Model

Published on: September 29, 2011

16.0K
Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making
11:51

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making

Published on: March 2, 2011

15.7K

Related Experiment Videos

Last Updated: Feb 7, 2026

Integrating Visual Psychophysical Assays within a Y-Maze to Isolate the Role that Visual Features Play in Navigational Decisions
07:09

Integrating Visual Psychophysical Assays within a Y-Maze to Isolate the Role that Visual Features Play in Navigational Decisions

Published on: May 2, 2019

6.5K
Studying Age-dependent Genomic Instability using the S. cerevisiae Chronological Lifespan Model
08:46

Studying Age-dependent Genomic Instability using the S. cerevisiae Chronological Lifespan Model

Published on: September 29, 2011

16.0K
Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making
11:51

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making

Published on: March 2, 2011

15.7K

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Gerontology

Background:

  • Aging is associated with cognitive decline, impacting perceptual decision-making.
  • The specific neurobiological mechanisms driving age-related changes in perception remain unclear.

Purpose of the Study:

  • To investigate the effects of aging on perceptual decision-making and binocular rivalry.
  • To elucidate the neurobiological underpinnings of age-associated alterations in visual perception.

Main Methods:

  • Two age groups performed perceptual tasks under continuous and intermittent stimulus presentation.
  • Participants reported spontaneous percept switches and made choices during binocular rivalry.

Main Results:

  • No significant age effect was found on the mean or cumulative frequencies of percept switch durations.
  • A significant age effect emerged in the coefficient of variation of percept durations.
  • Older adults showed a decline in percept alternation rate under intermittent presentation, especially with shorter inter-stimulus durations.

Conclusions:

  • Age-dependent changes in visual perceptual decisions are attributed to alterations in neural adaptation and noise levels.
  • Inhibition strength does not appear to be the primary factor in age-related perceptual decline.
  • Low-level neural property variations significantly influence age-dependent visual perception.