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Analysis of risk factors of lymph node metastasis in rectal neuroendocrine neoplasms using multicenter data
Gengzhou Wei1,2, Xingyu Feng1, Wei Wang3
1Department of General Surgery, Guangdong General Hospital; Guangdong Academy of Medical Sciences, Guangzhou, PR China.
Aim:
This study was conducted to analyze the risk factors associated with lymph node metastasis in rectal neuroendocrine neoplasms (NENs).
Materials & Methods:
A total of 419 patients with rectal NENs were enrolled. A univariate analysis of risk factors of lymph node metastasis was conducted using a χ2 test, and a multivariate analysis was conducted using a logistic regression analysis.
Results:
Univariate and multivariate regression analysis revealed that tumor size, G grade and the depth of tumor invasion were independent risk factors for lymph node metastasis (p < 0.05).
Conclusion:
Rectal NENs patients with a larger tumor size, deeper tumor invasion or a higher G grade had a higher risk of regional lymph node metastasis.
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