Related Experiment Video

Updated: Feb 7, 2026

Modified Heterotopic Abdominal Heart Transplantation and a Novel Aortic Regurgitation Model in Rats
13:32

Modified Heterotopic Abdominal Heart Transplantation and a Novel Aortic Regurgitation Model in Rats

Published on: June 2, 2023

2.7K

Impact of Abdominal Aortic Calcification Among Liver Transplantation Recipients

Yuki Imaoka1, Masahiro Ohira1,2, Ryosuke Nakano1

  • 1Department of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
|July 19, 2018
PubMed

Insights

High abdominal aortic calcification (AAC) is linked to poorer survival after liver transplantation (LT). This finding suggests AAC is an independent risk factor for liver transplant outcomes.

Area of Science:

  • Cardiovascular Medicine
  • Transplantation Surgery
  • Nephrology

Background:

  • Abdominal aortic calcification (AAC) is a known risk factor for cardiovascular and renal diseases.
  • The prognostic value of incidental AAC in liver transplantation (LT) recipients remains unclear.
  • Evaluating AAC's impact on post-LT survival and complications is crucial.

Purpose of the Study:

  • To investigate the association between abdominal aortic calcification (AAC) levels and outcomes in liver transplantation (LT) patients.
  • To determine if AAC is an independent predictor of post-transplant survival.

Main Methods:

  • Retrospective analysis of 156 LT patients from January 2007 to December 2014.
  • Patients were categorized into low (<100 mm³ Agatston score) and high (≥100 mm³ Agatston score) AAC groups.
  • Propensity matching and multivariate analysis were used to assess prognostic factors.

Main Results:

  • Liver transplant recipients with high AAC had significantly shorter survival times compared to those with low AAC (median 3.0 vs. 4.5 years, P < 0.01) even after propensity matching.
  • High AAC level (HR 2.2) and older donor age (HR 2.2) were identified as independent negative prognostic factors for overall survival.
  • Incidental AAC findings may have significant clinical implications for LT outcomes.

Conclusions:

  • Elevated abdominal aortic calcification is an independent unfavorable prognostic factor in liver transplantation.
  • Pre-transplant assessment of AAC may aid in risk stratification for LT candidates.
  • Further research is warranted to explore the mechanisms linking AAC to LT outcomes.

More Related Videos

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation08:43

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation

Published on: May 31, 2016

20.4K
Orthotopic Liver Transplantation in Rats18:25

Orthotopic Liver Transplantation in Rats

Published on: July 1, 2012

31.2K

Related Concept Videos

Impact of Groups on Groups01:19

Impact of Groups on Groups

Social psychologists analyze how groups influence one another, shaping social structures and interactions through both cooperation and competition. These dynamics manifest in various ways, ranging from economic partnerships to intergroup conflicts that shape societal structures and perceptions.Cooperation and Competition in Intergroup RelationsIntergroup relationships vary across contexts, sometimes fostering cooperation and mutual benefit while at other times leading to conflict and...
254
Abdominal Aorta01:25

Abdominal Aorta

Once the aorta traverses the diaphragmatic plane at the aortic hiatus, it is known as the abdominal aorta. This anatomical structure is positioned leftward of the spinal column, encased within a cocoon of adipose tissue behind the peritoneal cavity. It terminates at the L4 vertebra, where it splits into the common iliac arteries. Prior to this bifurcation, the abdominal aorta gives rise to several vital branches.
The celiac trunk, a singular artery, divides into the left gastric artery, which...
2.4K
Impact01:30

Impact

Impact occurs when two bodies collide, leading to the application of impulsive forces between them. Analyzing impact mechanics involves considering two colliding particles moving along a line known as the line of impact, which passes through their centers and is perpendicular to the contact plane.
When particles with different initial velocities collide, they induce deformation by applying equal and opposite impulses. At the point of maximum deformation, the particles move together with...
507
Ultrasound I: Abdominal Ultrasonography01:20

Ultrasound I: Abdominal Ultrasonography

Introduction:
Abdominal ultrasonography, commonly known as abdominal ultrasound, is a vital, non-invasive medical imaging technique widely used in healthcare.
Procedure:
This diagnostic tool allows the clinician to visually inspect internal structures within the abdomen, including vital organs such as the liver, gallbladder, pancreas, kidneys, and spleen.
The abdominal ultrasound process begins with applying a special gel to the patient's skin over the abdomen. This gel enhances the...
1.7K
Abdominal Regions and Quadrants01:19

Abdominal Regions and Quadrants

To promote clear communication, for instance, about the location of a patient's abdominal pain or a suspicious mass, anatomists and clinicians typically use imaginary lines to categorize the abdominopelvic cavity into either four quadrants or nine regions to identify organs in the cavity.
The simpler quadrants approach, which is more commonly used in medicine, subdivides the cavity with one horizontal and one vertical line that intersects at the patient's umbilicus (navel). The four...
17.8K
Impact of Groups on Individuals01:28

Impact of Groups on Individuals

Groups play a fundamental role in shaping individual behavior, as they establish norms that guide interactions and decision-making. Social psychology examines how individuals conform to group expectations, often adjusting their attitudes and actions to align with group norms. These norms can be formal, such as workplace policies, or informal, such as unspoken social expectations within a fraternity.Conformity and Social InfluenceConformity arises when individuals modify their behaviors or...
363