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Updated: Aug 6, 2026

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The Influence of Liver Resection on Intrahepatic Tumor Growth
Published on: April 9, 2016
Hepatic Carcinoma With Epithelial-Myoepithelial Differentiation and Metachronous Intrahepatic Recurrence Following
Ryo Nagao1, Tomoyuki Abe1, Masateru Yamamoto1
1Department of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Summary
Epithelial-myoepithelial carcinoma (EMC) of the liver is rare. This case highlights successful management of intrahepatic recurrence with repeat hepatectomies, offering a potential curative option for select patients.
Area of Science:
- Oncology
- Hepatobiliary Surgery
- Pathology
Background:
- Epithelial-myoepithelial carcinoma (EMC) is a rare malignant tumor typically found in salivary glands, characterized by biphasic epithelial and myoepithelial differentiation.
- Primary hepatic tumors exhibiting epithelial-myoepithelial differentiation are exceptionally rare, with their definition and clinical behavior poorly understood due to limited case reports.
- This study addresses the rarity of hepatic carcinoma within the myoepithelial carcinoma/epithelial-myoepithelial carcinoma (MEC/EMC) spectrum.
