Related Experiment Video
Updated: Feb 7, 2026

Using the Threat Probability Task to Assess Anxiety and Fear During Uncertain and Certain Threat
Published on: September 12, 2014
Complicated appendicitis wrongly diagnosed as nonspecific diarrhea: ways to decrease this continuous threat
Baruch Klin1,2, Leonid Zlotcavitch3, Oleg Lysyy4,5
1Department of Pediatric Surgery, Assaf Harofeh Medical Center, Zerifin, Israel - klin2@netvision.net.il.
Misdiagnosing complicated appendicitis as gastroenteritis in children leads to worse outcomes. Early surgical consultation and imaging are key to preventing delayed diagnosis of right lower quadrant pain.
Area of Science:
- Pediatric Surgery
- Diagnostic Imaging
- Gastroenterology
Background:
- Diagnosing right lower quadrant pain in pediatric patients presents diagnostic challenges.
- Appendicitis is frequently misdiagnosed as nonspecific diarrhea, leading to delayed treatment.
- This study investigates complicated appendicitis cases initially misdiagnosed as gastroenteritis.
Purpose of the Study:
- To analyze cases of complicated appendicitis misdiagnosed as nonspecific diarrhea in children and adolescents.
- To propose a policy to reduce misdiagnosis rates for right lower quadrant pain.
- To improve diagnostic accuracy for pediatric abdominal pain.
Main Methods:
- Retrospective analysis of three patient groups: appendectomy (Group 1), gastroenteritis (Group 2), and appendectomy after misdiagnosis of gastroenteritis (Group 3).
- Comparison of clinical presentation, laboratory values, and treatment outcomes.
- Evaluation of diagnostic tools including C-reactive protein (CRP), abdominal ultrasound (US), and computed tomography (CT).
Main Results:
- Group 3 (misdiagnosed appendicitis) experienced a more complicated clinical course.
- Patients in Group 3 exhibited higher fever, diffuse abdominal pain, repeat vomiting, and elevated CRP.
- Group 3 also showed longer surgery duration and recovery periods compared to other groups.
Conclusions:
- Atypical right lower quadrant pain with diarrhea, fever, vomiting, and elevated CRP warrants early surgical consultation.
- Abdominal ultrasound should be considered for unclear cases.
- CT scans are recommended for cases unresolved by initial assessments.
Related Concept Videos
Appendicitis-I: Introduction
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Stereotype Threat and Self-fulfilling Prophecies
Threats to Biodiversity
Decreasing Function
Appendicitis-II: Diagnostic Studies and Management
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Decreased Body Temperature

