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Updated: Feb 7, 2026

Transthoracic Echocardiography in Mice
Published on: May 28, 2010
Study on factors affecting local peak strain results in automatic functional imaging of transthoracic
Na Li1, Linbin Meng2, Yichen Wang3
1Function Department of Sichuan Integrative Medicine Hospital, Chengdu 610000, China.
Background:
To investigate the important impacting factors on the accuracy of local peak strain (RLS) in transthoracic echocardiography real-time tri-axial automatic functional imaging (AFI), to evaluate the clinical efficacy of AFI and to improve the accuracy of the results.
Methods:
From May 2016 to May 2017, 82 healthy volunteers were enrolled in the AFI examination, of which 22 were excluded and 60 were eligible. The excluded 22 patients were analyzed for exclusion reasons, and the results of the 60 eligible AFI results were studied focusing on the longitudinal left ventricular regional longitudinal peak systolic strain (RLS) in different methods of operation, to compare the results and accuracies of AFI by different influencing factors, and to find the most important ones.
Results:
The success rate of AFI for this group of subjects is 74%, and the exclusion reason is that the left ventricular segments cannot be fully displayed. Among eligible subjects, the main influencing factors on RLS were region of interest (ROI), aortic valve closure time adjustment and image frame rate selection. The differences of results obtained by different operations were statistically significant (P<0.05).
Conclusions:
The success rate of AFI for this group of subjects is 74%. The RLS results were influenced by multiple factors, which can be effectively avoided.
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