Related Experiment Videos
A "Smart Lock" for Preventing Hepatitis B Entry into Cells
Madeline Balzarini1, Thomas Kodadek1
1Department of Chemistry, The Scripps Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA.
Cell Chemical Biology
|July 21, 2018
Abstract:
In this issue of Cell Chemical Biology, Passioura et al. (2018) report another interesting application of the powerful random non-standard peptide integrated discovery (RaPID) screening method. They identify several high-affinity macrocyclic peptides for the sodium taurocholate co-transporting polypeptide (NTCP), the protein through which hepatitis B virus (HBV) enters the cell.