Related Experiment Video

Updated: Feb 7, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
10:28

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function

Published on: March 15, 2022

5.9K

Angina bullosa haemorrhagica: a systematic review and proposal for diagnostic criteria

U Ordioni1, M Hadj Saïd2, G Thiery3

  • 1Department of Oral Surgery and Odontology, APHM, Timone Hospital, Marseille, France; Centre Massilien de la Face, Marseille, France.

International Journal of Oral and Maxillofacial Surgery
|July 24, 2018
PubMed

Insights

Angina bullosa haemorrhagica (ABH) is poorly understood, with limited evidence. This review proposes diagnostic criteria to improve patient care for this condition.

Area of Science:

  • Oral Medicine
  • Dermatology
  • Pathology

Background:

  • Angina bullosa haemorrhagica (ABH) is a rare oral condition characterized by spontaneous blistering and hemorrhage.
  • Limited high-quality evidence exists regarding its epidemiological and etiological characteristics.

Purpose of the Study:

  • To critically review and synthesize existing literature on the epidemiological, etiological, clinical, histological, biological, and therapeutic aspects of ABH.
  • To propose diagnostic criteria for ABH based on a systematic literature review.

Main Methods:

  • Systematic literature search of PubMed, Science Direct, Web of Science, and Cochrane Library databases.
  • Eligibility assessment according to PRISMA statement.
  • Inclusion of 40 articles (1985-2016) describing 225 ABH cases.

Main Results:

  • Mean patient age was 55.4 years, with a female predominance (M:F ratio 0.7).
  • Palate was the most common site (66%); 82% had a triggering factor.
  • Symptomatic treatment yielded favorable outcomes, but recurrences were frequent (62%).

Conclusions:

  • ABH is characterized by a lack of robust scientific documentation and low-level evidence studies.
  • No clear aetiopathogenic associations with general pathologies or treatments were identified.
  • Proposed diagnostic criteria aim to enhance the management of ABH patients.

Keywords:
angina bullosa haemorrhagicadiagnosticoral mucosa blisterssystematic review

More Related Videos

Author Spotlight: Demonstrating Systematic Endobronchial Ultrasound to New Endoscopists05:22

Author Spotlight: Demonstrating Systematic Endobronchial Ultrasound to New Endoscopists

Published on: August 11, 2023

2.8K
Author Spotlight: Learning Systematic Bronchoscopy in a Simulation-Base Setting04:47

Author Spotlight: Learning Systematic Bronchoscopy in a Simulation-Base Setting

Published on: June 23, 2023

3.6K

Related Concept Videos

Criteria for Causality: Bradford Hill Criteria - II01:28

Criteria for Causality: Bradford Hill Criteria - II

The Bradford Hill criteria serve as guidelines for establishing causative links in epidemiological research. Beyond Strength, Consistency, Specificity, and Temporality, key criteria also include Biological Gradient, Plausibility, Coherence, Experiment, and Analogy. These principles assist scientists in assessing the likelihood of causation in complex biological contexts. Below is a summary of these concepts:
1.3K
Criteria for Causality: Bradford Hill Criteria - I01:30

Criteria for Causality: Bradford Hill Criteria - I

The Bradford Hill criteria are a group of principles that provide a framework to determine a causal relationship between a specific factor and a disease. There are nine criteria that are pivotal in assessing causality in epidemiological studies. Here's a closer look at Strength, Consistency, Specificity, and Temporality criteria with definitions and examples:
1.1K
Angina I: Introduction01:30

Angina I: Introduction

Definition and Symptoms: Angina (angina pectoris) is chest pain or discomfort caused by myocardial ischemia, which occurs when the heart muscle receives insufficient oxygen-rich blood. It typically manifests as pressing, squeezing, or crushing sensations in the chest and may radiate to the shoulders, arms, neck, jaw, or back.Primary Cause: In a healthy state, the coronary arteries can dilate (widen) to increase blood flow and meet the increased oxygen demand during physical activity or...
551
Angina II: Classification01:27

Angina II: Classification

Angina, also known as angina pectoris, is a chest pain resulting from diminished blood flow to the heart muscle and is often a symptom of coronary artery disease. Angina presents several variants with distinctive attributes, etiologies, and therapeutic approaches. The main types of angina include stable, unstable, variant (Prinzmetal's), microvascular, intractable, and silent ischemia.Stable angina is caused by atherosclerosis, which leads to the formation of plaques that narrow the coronary...
402
Angina IV: Management01:26

Angina IV: Management

IntroductionThe management of angina requires a comprehensive approach that includes pharmacological therapies, medical procedures, and lifestyle modifications.Pharmacological TherapiesAntiplatelet agents, such as aspirin, clopidogrel, prasugrel, and ticagrelor, play a pivotal role in preventing thrombus formation in patients with angina. These medications inhibit platelet aggregation and reduce the likelihood of myocardial infarction and other cardiovascular events.Anticoagulants, including...
297
Angina V: Nursing Management01:20

Angina V: Nursing Management

Angina, a symptom of myocardial ischemia, requires a structured nursing management approach to ensure effective care and prevent complications like myocardial infarction. Comprehensive nursing care involves assessing, diagnosing, planning, implementing interventions, and evaluating outcomes, all tailored to the individual patient's needs.Patient AssessmentNursing assessment begins with a detailed subjective evaluation of symptoms, which typically include chest pain or pressure radiating to the...
354