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Loss of H3K27me3 Imprinting in Somatic Cell Nuclear Transfer Embryos Disrupts Post-Implantation Development

Shogo Matoba1, Huihan Wang2, Lan Jiang3

  • 1Howard Hughes Medical Institute; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; RIKEN Bioresource Research Center, Tsukuba, Ibaraki 305-0074, Japan; Cooperative Division of Veterinary Sciences, Tokyo University of Agriculture and Technology, Fuchu, Tokyo 183-8509, Japan.

Cell Stem Cell
|July 24, 2018
PubMed

Keywords:
DNA methylationH3K27me3-dependent imprintinganimal cloningepigenetic reprogramminggenomic imprintingmouse embryosomatic cell nuclear transfer

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