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An end in sight? Xrn2 and transcriptional termination by RNA polymerase II
1a The Living Systems Institute , University of Exeter , Exeter , UK.
Transcription
|July 24, 2018
Abstract:
Every transcription cycle ends in termination when RNA polymerase dissociates from the DNA. Although conceptually simple, the mechanism has proven somewhat elusive in eukaryotic systems. Gene-editing and high resolution polymerase mapping now offer clarification of important steps preceding transcriptional termination by RNA polymerase II in human cells.
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