Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diffusion01:12

Diffusion

220.2K
Diffusion is the passive movement of substances down their concentration gradients—requiring no expenditure of cellular energy. Substances, such as molecules or ions, diffuse from an area of high concentration to an area of low concentration in the cytosol or across membranes. Eventually, the concentration will even out, with the substance moving randomly but causing no net change in concentration. Such a state is called dynamic equilibrium, which is essential for maintaining overall...
220.2K
Diffusion01:21

Diffusion

6.4K
Diffusion is a type of passive transport. In passive transport, a substance tends to move from an area of high concentration to an area of low concentration until the concentration is equal across the space. For example, take the diffusion of substances through the air. When someone opens a perfume bottle in a room filled with people, the perfume is at its highest concentration in the bottle and is at its lowest at the edges of the room. The perfume vapor will diffuse, or spread away, from the...
6.4K
Oral Hypoglycemic Agents: Sulfonylureas01:17

Oral Hypoglycemic Agents: Sulfonylureas

1.1K
Sulfonylureas are oral hypoglycemic agents utilized in treating type 2 diabetes. They are characterized by their unique sulfonylurea chemical structure. The family of sulfonylureas is divided into generations. First-generation sulfonylureas, including tolbutamide (Orinase), chlorpropamide (Diabinese), and tolazamide (Tolinase), trigger insulin release from pancreatic β cells and enhance peripheral tissues' insulin sensitivity. The second-generation members, such as glipizide...
1.1K
Weighted Mean00:57

Weighted Mean

6.4K
While taking the arithmetic, geometric, or harmonic mean of a sample data set, equal importance is assigned to all the data points. However, all the values may not always be equally important in some data sets. An intrinsic bias might make it more important to give more weightage to specific values over others.
For example, consider the number of goals scored in the matches of a tournament. While computing the average number of goals scored in the tournament, it may be more important to...
6.4K
Atomic Weight01:25

Atomic Weight

13.8K
Protons and neutrons have approximately the same mass, about 1.67 × 10-24 grams. Scientists arbitrarily define this amount of mass as one atomic mass unit (amu) or one Dalton. Electrons are much smaller in mass than protons, weighing only 9.11 × 10-28 grams, or about 1/1800 of an atomic mass unit. As a result, they do not contribute much to an element's overall atomic mass. This means that, when considering atomic mass, it is customary to ignore the mass of any electrons and...
13.8K
Mass and Weight01:19

Mass and Weight

15.4K
Mass and weight are often used interchangeably in everyday conversation. For example,  medical records often show our weight in kilograms, but never in the correct units of newtons. In physics, however, there is an important distinction. Weight is the pull of the Earth on an object. It depends on the distance from the center of the Earth. Weight dramatically varies if we leave the Earth's surface, unlike mass, which does not vary with location. On the Moon, for example, the...
15.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dietary conjugated linoleic acid in poultry diets and its implications for hatchability, egg quality and immune function: a review.

British poultry science·2026
Same author

Long term sexual outcomes of Mayer Rokitansky Küster Hauser Syndrome patients after Uncu-modified Davydov procedure.

Facts, views & vision in ObGyn·2023
Same author

Macroanatomical and histological study of the structure of intercornual gland in Abaza (Capra Aegagrus) and Gurcu (Capra Falconeri) goats breeds.

Folia morphologica·2020
Same author

Morphometric and macroanatomic examination of auditory ossicles in male wolves (Canis lupus).

Folia morphologica·2019
Same author

Beneficial Therapeutic Effects of Sildenafil on Bone Healing in Animals Treated with Bisphosphonate.

Nigerian journal of clinical practice·2018
Same author

Giant vascular eccrine spiradenoma of the leg: MR imaging findings.

Diagnostic and interventional imaging·2016

Related Experiment Video

Updated: Feb 7, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

4.3K

Reversible Focal Splenial Lesion on Diffusion-Weighted MRI in Sulfonylurea Intoxication.

K Aslan1, A V Polat1, G O Taskin2

  • 1Department of Radiology, University of Ondokuz Mayis, Faculty of Medicine, Samsun, Turkey.

Journal of the Belgian Society of Radiology
|July 25, 2018
PubMed
Summary

Diffusion-weighted imaging (DWI) revealed a rare, reversible lesion in the splenium of the corpus callosum (SCC) in a patient with severe hypoglycemia due to sulfonylurea intoxication. DWI successfully predicted the lesion

Keywords:
Poisonspoisoning

More Related Videos

Modeling Stroke in Mice: Focal Cortical Lesions by Photothrombosis
06:07

Modeling Stroke in Mice: Focal Cortical Lesions by Photothrombosis

Published on: May 6, 2021

7.7K
Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping
10:25

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping

Published on: September 25, 2019

49.4K

Related Experiment Videos

Last Updated: Feb 7, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

4.3K
Modeling Stroke in Mice: Focal Cortical Lesions by Photothrombosis
06:07

Modeling Stroke in Mice: Focal Cortical Lesions by Photothrombosis

Published on: May 6, 2021

7.7K
Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping
10:25

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping

Published on: September 25, 2019

49.4K

Area of Science:

  • Neurology
  • Radiology
  • Toxicology

Background:

  • Hypoglycemic brain injury prognosis depends on the affected brain area.
  • Diffusion-weighted imaging (DWI) can predict outcomes in hypoglycemic brain injury.
  • Isolated splenium of corpus callosum (SCC) lesions are rare in hypoglycemic brain injury.

Purpose of the Study:

  • To report a rare case of reversible SCC lesion in hypoglycemic brain injury.
  • To highlight the utility of DWI in diagnosing and predicting prognosis.
  • To discuss sulfonylurea intoxication as a cause of deep hypoglycemia.

Main Methods:

  • Case report of a 15-year-old female with attempted sulfonylurea suicide.
  • Performed DWI two hours after admission due to coma and severe hypoglycemia (10 mg/dl).
  • Monitored clinical recovery and performed follow-up DWI after treatment.

Main Results:

  • DWI showed diffusion restriction in the SCC upon admission.
  • The patient recovered consciousness and normalized blood glucose within 24 hours.
  • Follow-up DWI confirmed complete resolution of the SCC lesion within two days.

Conclusions:

  • DWI can identify reversible SCC lesions in hypoglycemic brain injury.
  • Sulfonylurea intoxication can cause isolated, reversible SCC lesions.
  • DWI plays a crucial role in predicting clinical outcomes of hypoglycemic brain injury.