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Updated: Feb 7, 2026

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Recent progress in analytical capillary isotachophoresis.

Zdena Malá1, Petr Gebauer1

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This review surveys analytical Isotachophoresis (ITP) studies from 2016-2018, highlighting its unique concentrating abilities for high-sensitivity analysis and its place among modern separation techniques.

Keywords:
Analytical electrophoresisIsotachophoresisReview

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Area of Science:

  • Analytical Chemistry
  • Separation Science

Background:

  • Analytical Isotachophoresis (ITP) is a powerful separation technique.
  • Recent advancements have focused on enhancing its sensitivity and applicability.
  • ITP offers unique concentrating capabilities valuable for trace analysis.

Purpose of the Study:

  • To provide a comprehensive review of analytical ITP studies published between 2016 and early 2018.
  • To assess the current standing of ITP within contemporary separation techniques.
  • To highlight the importance of ITP's concentrating capabilities in developing sensitive analytical methods.

Main Methods:

  • Literature review of scientific papers on analytical ITP.
  • Categorization of studies based on ITP theory, instrumentation, techniques, and applications.
  • Analysis of reviewed papers considering their nature, methods, and instrumentation.
  • Emphasis on the role of electrolyte system composition in ITP performance.

Main Results:

  • The review covers theoretical principles, instrumentation, techniques, and applications of ITP.
  • Analytical ITP is positioned as a valuable technique due to its high-sensitivity potential.
  • Specific examples and values are provided to illustrate the significance of electrolyte composition.

Conclusions:

  • Analytical ITP remains a relevant and promising technique for high-sensitivity analyses.
  • The unique concentrating power of ITP is a key factor driving its continued interest and application.
  • Further research and development in ITP instrumentation and electrolyte systems are crucial for its advancement.