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Updated: Feb 7, 2026

Bioelectric Analyses of an Osseointegrated Intelligent Implant Design System for Amputees
Published on: July 15, 2009
[Osseointegration click-on prosthesis following leg amputation]
Jan P M Frölke1,2, Ruud A Leijendekkers3, Henk van de Meent4
1Radboudumc, afd. Heelkunde, Nijmegen.
Osseointegration prostheses for leg amputation are safe and effective, with serious complications being rare. This treatment shows promise for amputees, including those with vascular disease.
Area of Science:
- Orthopedic surgery
- Biomedical engineering
- Rehabilitation medicine
Background:
- Osseointegration prostheses offer an alternative to traditional socket prostheses for leg amputees.
- Over 150 individuals in the Netherlands have received this treatment since 2009.
Purpose of the Study:
- To review the outcomes of osseointegration prostheses in the Netherlands.
- To discuss indications, contraindications, and early experiences with vascular amputees.
- To explore the future of osseointegration treatment.
Main Methods:
- Retrospective analysis of patient data.
- Review of clinical outcomes and complication rates.
- Case study of patients with vascular disease-related amputations.
Main Results:
- Serious complications like implant loosening or breakage are infrequent.
- Osseointegration is a viable option for a significant number of leg amputees.
- Initial experiences with vascular amputees are being documented.
Conclusions:
- Osseointegration prostheses demonstrate a favorable safety profile.
- The treatment is expanding to include patients with diverse amputation etiologies.
- Continued research and application are expected to advance osseointegration in the Netherlands.
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