Antimalarials - are they effective and safe in rheumatic diseases?

Area of Science:

• Pharmacology
• Rheumatology
• Immunology

Background:

• Antimalarial drugs (AD) are frequently used in rheumatology.
• Their key advantage is low toxicity, despite mild and slow therapeutic effects.

Purpose of the Study:

• To review the current knowledge on antimalarial drugs (AD).
• Focus on their mechanism of action, clinical use, toxicity, and pleiotropic effects in autoimmune diseases.

Main Methods:

• Literature review of existing studies on antimalarial drugs.
• Analysis of pharmacotherapy in autoimmune disease contexts.

Main Results:

• AD exhibit a favorable safety profile.
• Their pleiotropic effects contribute to managing autoimmune conditions.

Conclusions:

• Antimalarial drugs are valuable in treating autoimmune rheumatic diseases.
• Understanding their multifaceted effects can optimize patient outcomes.