Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Integration by Parts: Indefinite Integrals01:26

Integration by Parts: Indefinite Integrals

206
Integration by parts is a fundamental technique in calculus for evaluating integrals involving the product of two functions. It is particularly useful when direct integration is not feasible. The method is based on the product rule for differentiation, which states that the derivative of a product equals the derivative of the first function times the second, plus the first function times the derivative of the second. By integrating this identity and rearranging terms, the integration by parts...
206
Integration by Parts: Definite Integrals01:23

Integration by Parts: Definite Integrals

89
Definite integrals involving the product of two functions over a fixed interval can be evaluated using integration by parts. This method rewrites the integral as the difference of a product evaluated at the endpoints and a remaining definite integral that is often simpler to compute.A representative example is the definite integral of the inverse tangent function. Since there is no direct integration formula for arctan ⁡x, the integrand is rewritten as a product of arctan⁡ x and the...
89
EPS and iPS Cells in Disease Research01:21

EPS and iPS Cells in Disease Research

3.4K
Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...
3.4K
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

309
Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
309
Motor Units00:46

Motor Units

62.0K
A motor unit consists of two main components: a single efferent motor neuron (i.e., a neuron that carries impulses away from the central nervous system) and all of the muscle fibers it innervates. The motor neuron may innervate multiple muscle fibers, which are single cells, but only one motor neuron innervates a single muscle fiber.
62.0K
Motor Units01:13

Motor Units

8.2K
The motor unit is a fundamental component of the neuromuscular system and plays a crucial role in coordinating muscle contractions. It consists of a somatic motor neuron, which connects and controls multiple skeletal muscle fibers, forming a single functional segment. The axon of the motor neuron branches out and establishes synaptic connections known as neuromuscular junctions with individual muscle fibers within the motor unit.
Motor units come in different sizes, with smaller units...
8.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Non-adjacent dependency processing (or lack thereof) in bonobos: an artificial grammar experiment.

Royal Society open science·2025
Same author

Increased alertness and moderate ingroup cohesion in bonobos' response to outgroup cues.

PloS one·2024
Same author

Bo-NO-bouba-kiki: picture-word mapping but no spontaneous sound symbolic speech-shape mapping in a language trained bonobo.

Proceedings. Biological sciences·2022
Same author

Global quieting of high-frequency seismic noise due to COVID-19 pandemic lockdown measures.

Science (New York, N.Y.)·2020
Same author

Mapping Earth's deepest secrets.

Science (New York, N.Y.)·2020
Same author

Toxoplasma Calcium-Dependent Protein Kinase 1 Inhibitors: Probing Activity and Resistance Using Cellular Thermal Shift Assays.

Antimicrobial agents and chemotherapy·2018
Same journal

Increased 18F-FDG Avidity on PET/CT During Treatment for Rhabdomyosarcoma Confirmed to Be Mature Rhabdomyoblasts.

Journal of pediatric hematology/oncology·2026
Same journal

Assessment of Immunization Status Following Non-HSCT Chemotherapy-treated Pediatric Leukemia Survivors.

Journal of pediatric hematology/oncology·2026
Same journal

Frequent Use of Hematologic Testing in Children Admitted for Nonaccidental Trauma.

Journal of pediatric hematology/oncology·2026
Same journal

Unresponsive Systemic Mastocytosis in a Young AML With RUNX1::RUNX1T1 Fusion With Rare KIT c.1255_1257delGAC Mutation: A Clinical Deadlock.

Journal of pediatric hematology/oncology·2026
Same journal

Local Control and Survival Outcomes in Pediatric Nonrhabdomyosarcoma Soft Tissue Sarcoma: The Mayo Clinic Experience.

Journal of pediatric hematology/oncology·2026
Same journal

Diagnostic Pitfalls in Pediatric Acute Promyelocytic Leukemia: All-trans Retinoic Acid-Associated Hypercalcemia Mimicking Fungal Meningitis and the Risks of Azole Coadministration.

Journal of pediatric hematology/oncology·2026
See all related articles

Related Experiment Video

Updated: Feb 7, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
05:23

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

20.4K

Visual Motor Integration in Children With Sickle Cell Disease.

Robert F Newby1, Amanda Epping1, Jennifer A Geiger2

  • 1Medical College of Wisconsin/Children's Hospital of Wisconsin, Milwaukee, WI.

Journal of Pediatric Hematology/Oncology
|July 26, 2018
PubMed
Summary
This summary is machine-generated.

Children with sickle cell disease (SCD) have normal fine motor skills but impaired visual motor integration (VMI). This impacts early academic activities, highlighting the need for targeted support.

More Related Videos

A Method to Quantify Visual Information Processing in Children Using Eye Tracking
09:47

A Method to Quantify Visual Information Processing in Children Using Eye Tracking

Published on: July 9, 2016

18.2K
Breath Collection from Children for Disease Biomarker Discovery
06:09

Breath Collection from Children for Disease Biomarker Discovery

Published on: February 14, 2019

7.4K

Related Experiment Videos

Last Updated: Feb 7, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
05:23

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

20.4K
A Method to Quantify Visual Information Processing in Children Using Eye Tracking
09:47

A Method to Quantify Visual Information Processing in Children Using Eye Tracking

Published on: July 9, 2016

18.2K
Breath Collection from Children for Disease Biomarker Discovery
06:09

Breath Collection from Children for Disease Biomarker Discovery

Published on: February 14, 2019

7.4K

Area of Science:

  • Pediatric Neurology
  • Developmental Psychology

Background:

  • Children with sickle cell disease (SCD) often exhibit cognitive and academic challenges.
  • Visual motor integration (VMI) is crucial for academic success.

Purpose of the Study:

  • To compare VMI skills in children with SCD versus healthy siblings.
  • To investigate the impact of SCD on fine motor functioning.

Main Methods:

  • 105 participants (67 with SCD, 38 controls) were assessed.
  • Grooved Pegboard Test for manual dexterity.
  • Beery-Buktenica Developmental Test of VMI for graphomotor skills.

Main Results:

  • Children with SCD showed average manual dexterity and speed.
  • Graphomotor skills (VMI) were significantly impaired in children with SCD (P=0.04).
  • No significant difference in manual dexterity and speed between SCD patients and controls (P=0.617).

Conclusions:

  • Children with SCD possess average basic fine motor skills but impaired VMI.
  • Impaired VMI in SCD may affect early academic performance.
  • Further research into VMI deficits in SCD is warranted.