Related Experiment Video
Updated: Feb 7, 2026

Isolation Method for Long-Term and Short-Term Hematopoietic Stem Cells
Published on: May 19, 2023
Long-term survival of the cemented Müller CDH stem: a minimum follow-up of 10 years
Yves Salentiny1, Lukas Zwicky1, Peter E Ochsner1
1Clinic for Orthopedics and Trauma Surgery, Kantonsspital Baselland, Rheinstrasse 26, 4410, Liestal, Switzerland.
Insights
The cemented Müller CDH stem shows long-term survival comparable to other hip implants. However, titanium stems with low-viscosity cement significantly increase the risk of aseptic loosening and should be avoided.
Area of Science:
- Orthopedic surgery
- Biomaterials science
- Arthroplasty research
Background:
- Total hip arthroplasty (THA) for hip dysplasia is complex, often needing specialized stems.
- Müller straight stems offer good long-term outcomes, but data on cemented Müller CDH stems are limited.
Purpose of the Study:
- To evaluate the long-term survival of cemented Müller CDH stems.
- To identify risk factors for aseptic loosening.
- To assess the radiological outcomes of these implants.
Main Methods:
- Analysis of 95 cemented Müller CDH stems (stainless steel, CoCr, Ti) implanted between 1985-2005.
- Prospective clinical and radiological follow-up.
- Competing risk and multivariate regression models for survival and risk factor analysis.
Main Results:
- 15-year cumulative revision risk for aseptic loosening was 12.5%.
- Titanium (Ti) stems had a 24.5% revision risk, significantly higher than stainless steel (2.7%) and CoCr (12.9%).
- Risk factors for aseptic loosening included Ti stems with low-viscosity cement (HR 10.2) and axis deviation >3° (HR 3.8).
Conclusions:
- Cemented Müller CDH stem survival is comparable to other straight stems and uncemented options.
- Titanium Müller CDH stems demonstrate an elevated risk of aseptic loosening, similar to the original Ti Müller straight stem.
- The use of titanium Müller CDH stems is not recommended.
Introduction:
Total hip arthroplasty in patients with altered anatomy of the hip and femur, such as in congenital dysplasia of the hip, is challenging and often requires specially designed stems. Müller straight stems have shown excellent long-term results; however, long-term data on the analogous cemented Müller CDH stem are still missing. The aim of this study was to analyze long-term survival, identify potential risk factors for aseptic loosening, and analyze radiological outcome of the cemented Müller CDH stems.
Materials And Methods:
Between 01/1985 and 06/2005, 95 Müller CDH stems (Zimmer, Winterthur, Switzerland) made up of 3 different materials were cemented using 2 different bone cements: 38 of stainless steel/high-viscosity cement, 31 of a cobalt-chrome-based alloy (CoCr)/low-viscosity cement, and 26 of a titanium-based alloy (Ti)/low-viscosity cement. All patients had a prospective clinical and radiological follow-up according to the standards of our institution. The cumulative incidence for revision of the stem was calculated using a competing risk model. To identify demographic and implant-related risk factors for aseptic loosening of the stem, a multivariate regression model for competing risks was performed.
Results:
The cumulative risk of revision at 15 years was 12.5% (95% CI 6.6-20.5%) for aseptic loosening of the stem as endpoint, with marked differences for the various stem materials used: stainless steel 2.7% (0.2-12.3%), CoCr 12.9% (4.0-27.3%), and Ti 24.5% (9.6-43.1%). Regression modeling revealed that Ti stems in combination with low-viscosity cement (HR 10.2) and implantation with an axis deviation greater than 3° (HR 3.8) are risk factors for aseptic loosening.
Conclusions:
Long-term survival of the cemented Müller CDH stem is comparable to other Müller-type straight stems and uncemented implants. Similar to the original Ti Müller straight stem, the Ti Müller CDH stem also showed an increased risk for aseptic loosening and should, therefore, no longer be used.
Related Concept Videos
Hydration of Cement
Soundness of Cement
Portland Cement
Fineness of Cement
Direct...
Strength of Cement
For compressive strength tests, ASTM C 109-05 standards prescribe a cement-sand mix ratio of 1:2.75 and a water/cement ratio of 0.485 for making 2-inch cubes. These cubes are mixed, cast, and cured in saturated lime water at 23°C until testing. Flexural strength testing, outlined in...
Types of Cement I
Type I (Ordinary Portland Cement) is widely used for general construction where special properties are not required. It has moderate sulfate resistance and heat of hydration.
Type II (Modified Cement) offers moderate resistance to sulfate attack and a lower rate of heat development compared to Type I. It is suitable for structures in...

