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Related Concept Videos

Photoluminescence: Fluorescence and Phosphorescence01:23

Photoluminescence: Fluorescence and Phosphorescence

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Photoluminescence is a process where a molecule absorbs light energy and re-emits it in the form of light. This phenomenon occurs when a substance absorbs photons, promoting its electrons to higher energy level excited states, followed by a relaxation process in which the electrons return to their original ground state energy levels and emit light. Photoluminescence is widely observed in various materials, including semiconductors, and organic and inorganic compounds.
A pair of electrons in a...
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Atomic Fluorescence Spectroscopy01:29

Atomic Fluorescence Spectroscopy

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Atomic fluorescence spectroscopy (AFS) is an analytical technique that involves the electronic transitions of atoms in a flame, furnace, or plasma being excited by electromagnetic (EM) radiation. When these atoms absorb energy, they become excited and subsequently release energy as they return to their original state. This emitted light, or "fluorescence," is observed at a right angle to the incident beam. Both absorption and emission processes transpire at distinct wavelengths, which...
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Confocal Fluorescence Microscopy01:16

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Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
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Variables Affecting Phosphorescence and Fluorescence01:26

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Fluorescence and phosphorescence are essential phenomena in fields like analytical chemistry, biological imaging, and materials science, where they detect molecular properties and visualize cellular structures. Understanding the variables that influence these luminescent behaviors is crucial for maximizing accuracy and efficiency in their applications. These variables can broadly be grouped into chemical structure, solvent properties, and external conditions, each playing a distinct role in...
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Fluorescence and Phosphorescence: Instrumentation01:25

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Fluorometers and spectrofluorometers are two types of instruments used for measuring molecular fluorescence. These instruments differ in how they select excitation and emission wavelengths and the type of light sources they utilize. Fluorometers use absorption interference filters to choose excitation and emission wavelengths. The excitation source in a fluorometer is typically a low-pressure mercury vapor lamp that emits intense lines distributed throughout the ultraviolet and visible regions.
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Lewis Acids and Bases02:33

Lewis Acids and Bases

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In 1923, G. N. Lewis proposed a generalized definition of acid-base behavior in which acids and bases are identified by their ability to accept or to donate a pair of electrons and form a coordinate covalent bond.
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Citrate-Based Fluorescent Biomaterials.

Dingying Shan1, Jer-Tsong Hsieh2, Xiaochun Bai3

  • 1Department of Biomedical Engineering, Materials Research Institute, The Huck Institutes of The Life Sciences, The Pennsylvania State University, University Park, PA, 16802, USA.

Advanced Healthcare Materials
|July 27, 2018
PubMed
Summary
This summary is machine-generated.

Citrate-based fluorescent biomaterials offer a biocompatible and high-performance alternative to traditional agents for fluorescence imaging. These materials, derived from citric acid (CA), show promise for advanced biomedical applications.

Keywords:
bioimagingcarbon dotscitric aciddegradationfluorescence

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Area of Science:

  • Biomaterials Science
  • Chemical Biology
  • Medical Imaging

Background:

  • Fluorescence imaging requires advanced agents for monitoring biological species.
  • Traditional agents like quantum dots (QDs) and organic dyes present toxicity or performance limitations.
  • Citrate-based fluorescent biomaterials emerge as superior alternatives due to biocompatibility and high fluorescence.

Purpose of the Study:

  • To review recent advancements in citrate-based fluorescent materials.
  • To highlight design, synthesis, properties, and applications of these materials.
  • To guide future innovations in fluorescent biomaterials and biomedical technology.

Main Methods:

  • Literature review of citrate-based fluorescent materials.
  • Analysis of synthesis strategies and material properties.
  • Discussion of fluorescence mechanisms and biomedical applications.

Main Results:

  • Citrate-based materials (e.g., carbon dots, BPLPs) offer tunable fluorescence and good biocompatibility.
  • These materials overcome limitations of traditional fluorescent agents.
  • Diverse biomedical applications are being explored.

Conclusions:

  • Citrate-based fluorescent biomaterials represent a significant advancement in imaging technology.
  • Their biocompatibility, tunable properties, and cost-effectiveness make them highly promising.
  • Further research will drive innovation in next-generation fluorescent biomaterials and biomedical applications.