Two-dimensional speckle-tracking echocardiographic assessment of left ventricular mechanical synchrony in clinically

Yueh-Lun Hsu1, Hui-Pi Huang1

  • 1Institute of Veterinary Clinical Science, Veterinary School, National Taiwan University, Taipei, Taiwan, hphuang@ntu.edu.tw.

Insights

Clinically healthy cats exhibit left ventricular mechanical heterogeneity and synchrony. These findings establish normal ranges for these parameters in feline cardiology using advanced echocardiography techniques.

Area of Science:

  • Veterinary Cardiology
  • Cardiac Mechanics
  • Echocardiography

Background:

  • Ventricular heterogeneity and synchrony are linked to hypertrophic cardiomyopathy in humans.
  • Hypertrophic cardiomyopathy is a prevalent condition in domestic cats.
  • Understanding normal cardiac mechanics is crucial for diagnosing feline heart disease.

Purpose of the Study:

  • To establish the presence and normal range of left ventricular mechanical heterogeneity in healthy cats.
  • To determine the normal range of left ventricular mechanical synchrony in healthy cats.
  • To utilize two-dimensional speckle-tracking echocardiography for assessing these parameters.

Main Methods:

  • Prospective study including 34 clinically healthy cats.
  • Two-dimensional echocardiography and two-dimensional speckle-tracking echocardiography were performed.
  • Measurements included circumferential, radial, and longitudinal strain, strain rate, heterogeneity, and synchrony.

Main Results:

  • Segmental heterogeneity: circumferential 13.1%±5.9%, radial 19.1%±10.3%, longitudinal 15.4%±6.8%.
  • Transmural heterogeneity (circumferential): -14.3%±4.6%.
  • Left ventricular synchrony: circumferential 11.7±4.2 ms, radial 16.5±13.4 ms, longitudinal 19.4±8.5 ms. Inter-ventricular synchrony: -3.9±13.2 ms.

Conclusions:

  • Left ventricular mechanical heterogeneity and synchrony are present in clinically healthy cats.
  • Segmental longitudinal heterogeneity increases from apex to base.
  • Transmural circumferential heterogeneity decreases from endocardium to epicardium.

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