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Updated: Feb 7, 2026

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
Published on: October 20, 2016
Two-dimensional speckle-tracking echocardiographic assessment of left ventricular mechanical synchrony in clinically
1Institute of Veterinary Clinical Science, Veterinary School, National Taiwan University, Taipei, Taiwan, hphuang@ntu.edu.tw.
Insights
Clinically healthy cats exhibit left ventricular mechanical heterogeneity and synchrony. These findings establish normal ranges for these parameters in feline cardiology using advanced echocardiography techniques.
Area of Science:
- Veterinary Cardiology
- Cardiac Mechanics
- Echocardiography
Background:
- Ventricular heterogeneity and synchrony are linked to hypertrophic cardiomyopathy in humans.
- Hypertrophic cardiomyopathy is a prevalent condition in domestic cats.
- Understanding normal cardiac mechanics is crucial for diagnosing feline heart disease.
Purpose of the Study:
- To establish the presence and normal range of left ventricular mechanical heterogeneity in healthy cats.
- To determine the normal range of left ventricular mechanical synchrony in healthy cats.
- To utilize two-dimensional speckle-tracking echocardiography for assessing these parameters.
Main Methods:
- Prospective study including 34 clinically healthy cats.
- Two-dimensional echocardiography and two-dimensional speckle-tracking echocardiography were performed.
- Measurements included circumferential, radial, and longitudinal strain, strain rate, heterogeneity, and synchrony.
Main Results:
- Segmental heterogeneity: circumferential 13.1%±5.9%, radial 19.1%±10.3%, longitudinal 15.4%±6.8%.
- Transmural heterogeneity (circumferential): -14.3%±4.6%.
- Left ventricular synchrony: circumferential 11.7±4.2 ms, radial 16.5±13.4 ms, longitudinal 19.4±8.5 ms. Inter-ventricular synchrony: -3.9±13.2 ms.
Conclusions:
- Left ventricular mechanical heterogeneity and synchrony are present in clinically healthy cats.
- Segmental longitudinal heterogeneity increases from apex to base.
- Transmural circumferential heterogeneity decreases from endocardium to epicardium.
Abstract:
Ventricular heterogeneity and synchrony are associated with hypertrophic cardiomyopathy in humans. Hypertrophic cardiomyopathy is commonly observed in cats. The aim of this study was to determine the presence and normal range of left ventricular mechanical heterogeneity and synchrony in clinically healthy cats using two-dimensional speckle-tracking echocardiography. Thirty-four clinically healthy cats were included in this prospective study. Two-dimensional echocardiography and two-dimensional speckle-tracking echocardiography were performed on all cats. Echocardiographic parameters, including circumferential, radial, and longitudinal strain and strain rate, heterogeneity, and synchrony, were measured. Segmental heterogeneity values in the circumferential, radial, and longitudinal directions were 13.1%±5.9%, 19.1%±10.3%, and 15.4%±6.8%, respectively. Transmural heterogeneity was -14.3%±4.6% in the circumferential direction. Left ventricular synchrony values in the circumferential, radial, and longitudinal directions were 11.7±4.2, 16.5±13.4, and 19.4±8.5 ms, respectively. Inter-ventricular synchrony was -3.9±13.2 ms. Left ventricular heterogeneity and synchrony were noted in clinically healthy cats; segmental heterogeneity, which is characterized as longitudinal, progressively increased from the apical to the basal segments, while transmural heterogeneity, which is characterized as circumferential, progressively decreased from the endocardium to the epicardium.
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