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Area of Science:

  • Otolaryngology
  • Rhinology
  • Olfactory Neuroscience

Background:

  • Chronic rhinosinusitis (CRS) frequently causes olfactory dysfunction, impacting quality of life.
  • Endoscopic sinus surgery (ESS) is a primary treatment for CRS, but its effect on olfactory function requires detailed analysis.

Purpose of the Study:

  • To investigate the pattern of olfactory function recovery after ESS in CRS patients.
  • To correlate olfactory function changes with objective measures like CT scans and patient-reported symptoms.

Main Methods:

  • An observational study involving 34 CRS with nasal polyps (CRSwNP) and 14 CRS without nasal polyps (CRSsNP) patients.
  • Preoperative and 1, 3, and 6-month postoperative assessments included T&T olfactory tests, visual analog scale (VAS) for olfaction, SNOT-20 scores, and Lund-Mackay CT scores.

Main Results:

  • Significant improvements in olfactory function and SNOT-20 scores were observed within six months for both CRSwNP and CRSsNP groups.
  • Patients with preoperative anosmia showed the greatest improvement. Olfactory scores correlated significantly with CT scores in CRSwNP patients.
  • No significant olfactory recovery was noted at 1 and 3 months post-surgery in the CRSsNP group.

Conclusions:

  • ESS demonstrates therapeutic effects on olfactory function lasting up to six months, particularly beneficial for CRSwNP patients.
  • While olfactory improvements plateau around three months, continued recovery is observed between three and six months post-ESS.
  • The findings support ESS as an effective intervention for improving olfaction in specific CRS patient populations.