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Updated: Feb 7, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
Personalized behavior change program for glaucoma patients with poor adherence: a pilot interventional cohort study
Paula Anne Newman-Casey1, Leslie M Niziol1, Chamisa K Mackenzie1
11Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, 1000 Wall Street, Ann Arbor, MI 48105 USA.
This pilot study tested a personalized intervention combining reminders and motivational interviewing to improve medication adherence in glaucoma patients. The intervention aims to enhance chronic disease management for non-adherent individuals.
Area of Science:
- Ophthalmology
- Behavioral Science
- Health Services Research
Background:
- Glaucoma medication non-adherence affects about 50% of patients.
- Reminder systems and motivational interviewing (MI) have improved adherence in other chronic conditions.
- A personalized intervention was piloted to address medication adherence in glaucoma.
Purpose of the Study:
- To pilot a personalized intervention for glaucoma patients with poor medication adherence.
- To assess the impact of reminders and MI-based counseling on medication adherence.
- To evaluate changes in clinical outcomes and psychosocial mediators of adherence.
Main Methods:
- 57 non-adherent glaucoma patients were enrolled.
- Adherence was monitored for 2 years using electronic monitors, self-report, and pharmacy refills.
- Intervention included 3 months of reminders and 6 months of MI counseling via the eyeGuide system.
Main Results:
- The primary outcome is the change in medication adherence.
- Secondary outcomes include intraocular pressure (IOP) and IOP fluctuation.
- Psychosocial mediators like competence and satisfaction were also assessed.
Conclusions:
- This pilot study offers insights into personalized healthcare for non-adherent glaucoma patients.
- Findings will inform strategies to better support chronic disease management.
- Participant feedback will refine the counseling program for future improvements.
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