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[Effect of cytochrome c on bioenergetic processes in the liver in severe compression trauma]
Abstract:
After severe mechanical trauma of rat soft tissue content of ATP, total adenine nucleotides, amounts of "energy charge" of the adenine nucleotide system and cytochrome c were decreased in liver tissue, while content of AMP and Pi was increased. Parenteral administration of cytochrome c at a dose of 10 mg/kg into animals after the trauma normalized the energy processes in liver tissue and increased the content of endogenous cytochrome c.