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Updated: Feb 7, 2026

Application of Ultrasound and Shear Wave Elastography Imaging in a Rat Model of NAFLD/NASH
Published on: April 20, 2021
Establishing Normal Values for Shear-Wave Elastography of the Renal Cortex in Healthy Adults
Ranjit S Sandhu1, James Shin1, Natasha E Wehrli1
1Department of Radiology, Weill Cornell Medical College, NY 10065, USA.
Background:
Shear-wave elastography of the kidney has emerged as a potential clinical application of this novel imaging tool. However, normal velocity values for shear-wave elastography involving the cortex of healthy kidneys have not been definitively established, and both inter- and intraobserver reliability has yet to be comprehensively evaluated.
Methods:
This prospective study involved ultrasound examination of 11 healthy adults. Shear-wave velocity values were obtained at the renal cortex in the longitudinal and transverse planes by both junior (fellow) and senior (attending) radiologists.
Results:
The mean shear-wave velocity values ranged between 2.82 and 2.9 m/s, which did not vary significantly between observers (junior vs. senior) or method of measurement (longitudinal vs. transverse planes), P = 0.533. However, there was a wide variation for these measurements (0.51-4.99 m/s). Separate analysis of the measurement depth demonstrated no statistically significant association with the shear-wave velocity values, P = 0.477.
Conclusion:
Our results agree with previous publications and help establish normal shear-wave velocity values and their range for the renal cortex in adults.
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