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Assessing Mitochondrial Function in Sciatic Nerve by High-Resolution Respirometry
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Ultrasonographic Reference Values for Assessing Normal Sciatic Nerve Ultrasonography in the Normal Population.

Jun Chen1,2, Jiapeng Liu1, Jiao Zeng1

  • 1Department of Neurology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou Province, China.

Journal of Medical Ultrasound
|August 2, 2018
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Summary

High-resolution ultrasonography (HRUS) established normal sciatic nerve cross-sectional areas (CSAs) in 200 healthy adults. These reference values aid in diagnosing lower extremity nerve conditions.

Keywords:
Cross-sectional areahigh-resolution ultrasonographynerve lesionperipheral nervesciatic nervethe lower extremity peripheral nerve

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Area of Science:

  • Neurology
  • Medical Imaging
  • Anatomy

Background:

  • High-resolution ultrasonography (HRUS) is increasingly used for peripheral nerve characterization.
  • Established reference standards for lower extremity nerves, particularly the sciatic nerve, are lacking.
  • Accurate normative data is crucial for diagnosing and managing peripheral neuropathies.

Purpose of the Study:

  • To measure the cross-sectional areas (CSAs) of the sciatic nerve in a healthy adult population using HRUS.
  • To establish reference values for normal sciatic nerve CSAs.
  • To provide foundational data for the clinical application of HRUS in lower extremity nerve assessment.

Main Methods:

  • 200 healthy volunteers (18-80 years) were enrolled, with 400 lower extremities assessed.
  • Volunteers were categorized into young (18-30), middle (31-60), and old (61-80) age groups.
  • HRUS was employed to measure sciatic nerve CSAs at specific anatomical sites, recording age, sex, height, and weight.

Main Results:

  • The mean sciatic nerve CSAs were 0.527 ± 0.028 cm² at the greater sciatic notch (GS) and 0.444 ± 0.026 cm² at the mid-popliteal fossa (MPF).
  • Sciatic nerve CSAs showed correlation with participant height and weight.
  • No significant CSA differences were found across age groups, but women exhibited smaller CSAs than men (P < 0.05).

Conclusions:

  • HRUS is a reliable method for assessing peripheral nerves, including the sciatic nerve.
  • This study provides essential reference values for normal sciatic nerve CSAs.
  • These normative data will support the diagnosis, treatment, and prognosis of peripheral nerve disorders affecting the lower extremities.