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Paraneoplastic Sweet's syndrome
Daniela Gomes Cunha1, Gabriella Campos-do-Carmo1, Julia Macchione Marujo1
1Oncological Dermatology Service, Instituto Nacional do Câncer, Rio de Janeiro (RJ), Brazil.
Anais Brasileiros De Dermatologia
|August 2, 2018
Summary
Sweet's syndrome is a rare skin condition with unknown causes, often linked to other diseases. This case highlights a rare instance of paraneoplastic Sweet's syndrome associated with cervical cancer.
Area of Science:
- Dermatology
- Oncology
Background:
- Sweet's syndrome is a rare neutrophilic dermatosis.
- Its pathogenesis remains largely unknown.
- It is associated with infections, autoimmune diseases, inflammatory bowel diseases, vaccination, medications, and neoplasms.
Observation:
- Hematologic malignancies are most commonly linked to paraneoplastic Sweet's syndrome.
- Solid tumors, including genitourinary tract tumors, can occasionally present with this condition.
- A rare case of paraneoplastic Sweet's syndrome in the context of cervical cancer is presented.
Findings:
- This report details a rare association between cervical cancer and paraneoplastic Sweet's syndrome.
- It underscores the potential for Sweet's syndrome to manifest as a paraneoplastic phenomenon in gynecologic malignancies.
Implications:
- This case expands the understanding of paraneoplastic syndromes related to solid tumors.
- It suggests that Sweet's syndrome should be considered in the differential diagnosis of patients with cervical cancer presenting with characteristic skin lesions.
- Further research is warranted to elucidate the mechanisms underlying this association.
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